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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 69 for Urology

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  • Study status: Open/Status Unknown
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  1. Use of Tamsulosin to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

    Rochester, MN

  2. A Study to Evaluate 177Lu-PSMA-R2 in Patients with PSMA Positive Progressive, Metastatic, Castration Resistant Prostate Cancer

    Rochester, MN

  3. Study to Evaluate the Efficacy/Safety of IPI-549 in Combination With Nivolumab in Patients With Advanced Urothelial Carcinoma (MARIO-275)

    Scottsdale/Phoenix, AZ

  4. A Study of Proton Radiation Divided into Fewer Doses for Low Risk Prostate Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer

    Scottsdale/Phoenix, AZ

  6. A Study of Apalutamide in Participants With High‑Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study of the Effectiveness of Transvaginal Administration of Botulinum-A Toxin for the Treatment of Women with Over Active Bladder (OAB) Syndrome

    Jacksonville, FL

  8. A Study to Evaluate the Feasibility of Daily, Long-Term, Intermittent Fasting for Men on PSA Surveillance Following Radical Prostatectomy

    Rochester, MN

  9. MR-Guided Cryoablation of Prostate Bed Recurrences

    Rochester, MN

  10. A Study of Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 With or Without Bacillus Calumette-Guerin (BCG) in BCG Unresponsive Bladder Cancer That Has Not Invaded Into the Muscle Wall of the Bladder

    Scottsdale/Phoenix, AZ

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