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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 49 for Dermatology

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  • Study status: Open/Status Unknown
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  1. Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Study of VE800 and Nivolumab in Patients With Selected Types of Advanced or Metastatic Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  3. A Study to Evaluate UV1 Vaccination Plus Nivolumab and Ipilimumab in Treatment of Melanoma

    Scottsdale/Phoenix, AZ

  4. Hypertrophic Scar Prevention by Novel Topical Gel Application

    Rochester, MN

  5. A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. Ipilimumab and Nivolumab as Adjuvant Treatment of Mucosal Melanoma

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  7. Development of an Evidence-Based Decision Aid for Acne Treatment

    Rochester, MN

  8. A Study to Collect Long-Term Data on Pediatric Cutaneous Mastocytosis

    Rochester, MN

  9. A Study to Evaluate Storage and Utilization of Human Skin in Research

    Jacksonville, FL

  10. Study to Analyze the Metabolic Environment in Preventing Atopic Dermatitis

    Rochester, MN

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