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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 20 for Clinical Genomics

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  • Study status: Open/Status Unknown
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  1. A Study to Analyze Whole Methylome for Identification of Epigenetic Variations in Undiagnosed Congenital Disorders

    Rochester, MN

  2. Visual Outcomes in Patients with Neurofibromatosis Type 1

    Rochester, MN

  3. A Study to Develop a Cohort Database and Study Platform in Breast Cancer Survivors Using Multiscale Omics

    Rochester, MN

  4. GENetic Risk Estimation of Breast Cancer Prior to Decisions on Preventive Therapy Uptake, Risk Reducing Surgery or Intensive Imaging Surveillance

    Albert Lea, MN, Austin, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. A Study to Evaluate Return of Pharmacogenomic Results Through Direct-to-Consumer Online Portal: Consumer Experiences

    Rochester, MN

  6. A Study on Mayo Clinic Patients with Friedreich Ataxia

    Rochester, MN

  7. A Study of Clinical Symptoms in PMM2 Patients Affected by mtDNA Variants and Haplotypes

    Rochester, MN

  8. North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

    Rochester, MN

  9. APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

    Scottsdale/Phoenix, AZ

  10. A Time Study of the Microbiome in Colorectal Cancer Subjects

    Rochester, MN

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