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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-46 of 46 for General Surgery

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  • Study status: Open/Status Unknown
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  1. Clinical Outcomes and Quality of Life Measures in Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms

    Rochester, MN

  2. A Study of Blood Clotting Response in Patients with a Traumatic Injury

    Rochester, MN

  3. Cardiac Outcomes after Pectus Excavatum Repair

    Scottsdale/Phoenix, AZ

  4. Analysis of Outcomes in Sarcoma Reconstruction Using Intraoperative Fluorescence Angiography

    Jacksonville, FL

  5. A Study to Evaluate Same Day Discharge Post-mastectomy with/without Alloplastic Breast Reconstruction

    Rochester, MN

  6. A Study of the Bacteria found in Cancerous and Non-cancerous Breast Tissue

    Rochester, MN

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