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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 46 for General Surgery

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Safety of the Goldilocks Procedure with Implant-Based Reconstruction

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Toward an Objective Assessment of Surgical Outcomes and Facial and Body Deformity Using Eyetracking Technology

    Rochester, MN

  3. Comparison of Treatment Options for Achalasia

    Rochester, MN

  4. American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

    Jacksonville, FL

  5. Study of Breast Cancer Risk Assessment in Female Patients with Benign Breast Disease

    Rochester, MN, Jacksonville, FL

  6. A Study of Tumor Excision with Inferior Vena Cava Resection and Reconstruction Outcomes

    Rochester, MN

  7. A Study to Evaluate Neoadjuvant Chemotherapy on the Peripheral Blood Immune Phenotype in Patients with Operable Breast Cancer

    Rochester, MN

  8. A Study to Analyze the Detection of Plasma DNA Methylation in Peripheral Blood from Patients with Hepatocellular Carcinoma

    Rochester, MN

  9. Analysis of the Cardiac, Aorta and Carotid Artery Walls for Hemodynamic Monitoring in the Intensive Care Unit

    Jacksonville, FL

  10. A Study of the Ability to Predict Lymphedema Development Following Axillary Surgery for Breast Cancer and Its Effects on Patient Survivorship

    Jacksonville, FL

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