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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 46 for General Surgery

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Tranexamic Acid (TXA) Versus Placebo to Reduce Perioperative Blood Transfusion in Patients Undergoing Liver Resection

    Rochester, MN

  2. A Study to Examine Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection

    Jacksonville, FL

  3. A Study of Intravital Microscopy (IVM) in Human Solid Tumors

    Jacksonville, FL

  4. Post-Surgical Based Efforts to Reduce Preventable Readmissions and Optimize Length of Stay

    Rochester, MN

  5. Clinical Outcomes After Re-operation for Groin Pain due to Inguinal Herniorrhaphy

    Rochester, MN

  6. A Study to Assess Outcomes Based on Different Surgical Approaches to Minimally-invasive Gallbladder Surgery

    Rochester, MN

  7. Aggressive Malignancy PDX (Avatar) and Cryopreservation Program

    Rochester, MN

  8. Database of All Patients with Peritoneal Surface Malignancies Treated at Mayo Clinic

    Rochester, MN

  9. Outcomes of Open and Endovascular Repair for Ruptured and Non-Ruptured Internal Iliac Artery Aneurysms

    Rochester, MN

  10. Breast Cancer: Can We Predict Pathological Complete Response following Neoadjuvant Treatment?

    Scottsdale/Phoenix, AZ

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