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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 43 for Psychiatry and Psychology

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  1. Chronic Pain Biobank

    Jacksonville, FL

  2. A Study of Dihydropyrimidine Dehydrogenase Function in Neural Development and Function

    Rochester, MN

  3. A Study to Evaluate Treatment of Delayed Sleep-Wake Phase Syndrome with Melatonin in Patients with Comorbid Alcohol Use Disorders

    Rochester, MN

  4. A Study Evaluating the Prevalence, Incidence and Predictors for Development of the Impulse Control Disorders in Patients with Prolactinomas Treated with Dopamine Agonist Therapy

    Rochester, MN, Jacksonville, FL

  5. Pediatric Pain Rehabilitation Program

    Rochester, MN

  6. Attitudes and Beliefs About Gene Transfer Therapy in Adults with Cocaine Use Disorder

    Rochester, MN

  7. A Study to Build Translational Science through an Online Social Media Community Partnership Among Minnesota Communities, the CTSA Community Engagement Programs at Mayo Clinic and the University of Minnesota

    Rochester, MN

  8. A Study to Evaluate the Use of a Daily Diary to Guide Patient Care in Patients at RIsk of Suicide

    Eau Claire, WI

  9. Neuropsychological and Behavioral Testing in Young Patients with Cancer

    Rochester, MN

  10. A Study to Evaluate the Prevalence and Impact of Eating Disorders Among Patients with Inflammatory Bowel Disease

    Jacksonville, FL

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