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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 266 for Digestive Diseases

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  • Study status: Open/Status Unknown
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  1. Futibatinib and Pembrolizumab for the Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer

    Rochester, MN

  2. A Study to Evaluate Budesonide in Patients with Immune Mediated Enteropathies

    Rochester, MN

  3. A Study to Evaluate the Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia

    Rochester, MN

  4. A Study to Assess the Effects of the Minnesota Medical Technologies Anal Insert Device in Fecal Incontinence

    Rochester, MN

  5. Prospective, Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Symptomatic Celiac Disease Patients

    Rochester, MN

  6. A Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

    Rochester, MN

  7. A Study of Circulating Nucleic Acid Tumor Markers Found in Different Components of Blood

    Rochester, MN

  8. A Study to Develop and Validate Hybrid Molecular Imaging to Transform the Care of Hepatocellular Carcinoma Patients

    Rochester, MN

  9. A Study of Colesevelam in Fecal Incontinence

    Rochester, MN

  10. An Extension Study of Oral Ozanimod for Moderately-to-Severely Active Crohn's Disease

    La Crosse, WI

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