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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 217

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  • Study status: Open/Status Unknown
  • Healthy Volunteer: Accepts healthy volunteers
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  1. Respiratory Muscle Contribution to Blood Pressure During Exercise

    Rochester, MN

  2. A Study of Mechanisms of Altered Ventilatory Control in Heart Failure

    Rochester, MN

  3. A Study of the Diagnostic Performance of the Nonlinear Elasticity Parameter Mapping Method with Suspicious Breast Masses

    Rochester, MN

  4. Effect of Fasting, Endogenous GLP-1 Secretion on B-cell Response to Intravenous Glucose

    Rochester, MN

  5. Evaluating the Effectiveness of Apremilast in the Treatment of Subjects with Canker Sores

    Jacksonville, FL

  6. A Study to Evaluate Electrical Impedance Myography as an Outcome Measure in Myositis

    Jacksonville, FL

  7. A Study to Evaluate Individualized Lifestyle Intervention for Obesity Management Based on Obesity Phenotypes

    Rochester, MN

  8. Body Weight-Based Interval Training in Sedentary Overweight and Obese Adults

    Rochester, MN

  9. A Study of Anterior Cruciate Ligament Injury and Rehabilitation

    Rochester, MN, Minneapolis, MN

  10. Diffusion Tensor Imaging (DTI) in Plastic Surgery Surgical Planning

    Rochester, MN


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