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Clinical Studies


  • IL-4 & Insulin Resistance in Patients with Atopic Dermatitis Scottsdale/Phoenix, Ariz.

    The objective of this study is to assess the metabolic effect of systemic inhibition of IL-4 signaling on insulin sensitivity in patients with atopic dermatitis by comparing in vivo evaluations of insulin sensitivity in subjects on dupilumab vs. subjects matched for similar adiposity, with atopic dermatitis, but without dupilumab therapy.


  • Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity- AIM 1 Scottsdale/Phoenix, Ariz.

    This study is being done to better understand the relationship between inflammation in your AT, abnormal deposition of fat around your liver and how this affects its appearance and function and ultimately insulin resistance.

Closed for Enrollment

  • Heritability of Diabetes-related DNA Methylation in Latinos Scottsdale/Phoenix, Ariz., Rochester, Minn.

    The purpose of this study is to find the inheritable changes in genetic makeup that are related to the development of type 2 diabetes in Latino families.

  • Immunomodulatory Role of Eosinophils in Determining Inflammation and Insulin Sensitivity in Human Adipose Tissue- Aims 1&2 Scottsdale/Phoenix, Ariz.

    This study is being done to better understand the relationship between inflammation and insulin resistance in your Adipose (fat) Tissue .

  • Investigating the Effect of Obesity on Eosinophil Recruitment in Human Adipose Tissue Scottsdale/Phoenix, Ariz.

    To determine whether EOS recruitment in AT is impaired during obesity. Therefore, we hypothesize that chronic, low-grade inflammation of AT initiates epigenetic modifications in EOS and/or in AT, thereby impairing the recruitment of eosinophils.

  • Molecular Regulation of Muscle Glucose Metabolism Scottsdale/Phoenix, Ariz.

    This protocol is being conducted to determine the mechanisms responsible for insulin resistance, obesity and type 2 diabetes.

  • Role of Eosinophils in Human Adipose Tissue Metabolism (REHATM) Scottsdale/Phoenix, Ariz.

    This study aims to assess adipose tissue-eosinophil content and adiopose tissue metabolism 3 months after endoscopic gastroplasty weight loss procedure.

  • Sangre Por Salud Biobank Rochester, Minn., Scottsdale/Phoenix, Ariz.

    There are two purposes for this project.

    • One purpose of this project is to develop information about Latinos in the Maricopa County area who may be interested in participating in future research studies about health.

    • A second purpose is that researchers at Mayo Clinic are developing a new research resource called a Biobank. A Biobank is a collection of blood samples and other information. Participants in the Biobank provide samples of blood, complete a health questionnaire, and allow access to medical records now and in the future. A Biobank is as a library for researchers; instead of having to look for volunteers for each new project, researchers can use samples from the Biobank as well as share information already collected.