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  • Diet and Relapses in Multiple Sclerosis Rochester, Minn.

    The purpose of this research study is to better understand if diet and metabolism are connected with MS relapses and disease progress in patients with pediatric-onset MS.

  • Patient-Family Views on Pediatric MS Research Needs, Outcomes, and Methods Rochester, Minn.

    The primary purpose of this study is to determine patients' and families' priorities regarding clinical research studies and perceived barriers to pediatric onset multiple sclerosis (POMS) patients/family participation in research and interventional therapeutic studies.

     

Closed for Enrollment

  • Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis Rochester, Minn.

    The purpose of this study is to better understand multiple sclerosis (MS) in children and adolescents, to learn if it differs from adult MS and to investigate if genes or environmental exposures or a combination of both put children and adolescents at risk for getting MS.

  • Microbiomes in Pediatric Multiple Sclerosis Rochester, Minn.

    The objective of this study is to understand how commensal (the living together of two organisms in a relationship that is beneficial to one and has no effect on the other) bacteria are associated with MS.

  • Novel MRI Markers in Pediatric White Matter Disease Rochester, Minn.

    The purpose of this study is to better understand specific MRI characteristics of different pediatric disorders affecting the brain using new MRI analysis and imaging techniques to detect and understand subtle changes in specific parts of the brain.

  • Novel Structural and functional connectivity MRI Markers in Multiple Sclerosis Rochester, Minn.

    The purpose of this study is to develop quantitative approaches of analyzing multimodal MRI acquisitions with the goal to improve cortical lesion detection in all stages in MS, and to understand the interplay between cortical lesions, white matter lesions and functional connectivity network disruptions.

     

  • Treatment Adherence in Pediatric Multiple Sclerosis Rochester, Minn.

    Disease modifying therapies (DMT) are widely used for children and adolescents with MS. Nonetheless, many pediatric patients continue to relapse and therefore require changes in therapy. We designed this research study to learn more about medication use in children and adolescents with MS. We are also interested in learning what a behavioral feedback intervention can tell us about adherence to medicine. Finally, we hope this research project will inform the way we provide clinical care for children and adolescents with MS.

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