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  • Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA) (COLCORONA) Rochester, Minn., Jacksonville, Fla. This is a phase 3, multi-center, randomized, double-blind, placebo-controlled multicenter study to evaluate the efficacy and safety of colchicine in adult patients diagnosed with COVID-19 infection and have at least one high-risk criterion. Approximately 6000 subjects meeting all inclusion and no exclusion criteria will be randomized to receive either colchicine or placebo tablets for 30 days.
  • Expanded Access to Mepolizumab for Patients with Hypereosinophilic Syndrome Scottsdale/Phoenix, Ariz., Rochester, Minn.

    The purpose of this study is to provide a mechanism for expanded access to mepolizumab therapy for eligible patients with Hypereosinophilic Syndrome (HES).

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  • Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA) (COLCORONA) Scottsdale/Phoenix, Ariz. This is a phase 3, multi-center, randomized, double-blind, placebo-controlled multicenter study to evaluate the efficacy and safety of colchicine in adult patients diagnosed with COVID-19 infection and have at least one high-risk criterion. Approximately 6000 subjects meeting all inclusion and no exclusion criteria will be randomized to receive either colchicine or placebo tablets for 30 days.
  • PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study Scottsdale/Phoenix, Ariz.

    The purpose of this study is to evaluate several interventions given to participants with severe asthma. Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.

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