Mayo Clinic Drug Allergy Repository


About this study

The purpose of this study is to build a Mayo Clinic registry of data and biobank from subjects with drug allergy. The data collected will include demographic, diagnostic, and health data on a large group of patients to discover novel drug allergy diagnostic methods.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Male and females, ≥ 18 years of age.
  • Adults identified by a specialist as having a potential immunologically mediated reaction to a drug or externally administered substance during an acute event (i.e., perioperative anaphylaxis, drug challenge, etc.) or diagnosed by in-vitro and/or in-vivo testing after a reaction has occurred.
  • Subjects must provide informed consent. For each subject included, a control will be recruited: a patient exposed to the causal agent without evidence of an immediate drug allergy or having a negative drug allergy test/ drug challenge.

Exclusion Criteria:

  • Male and female, < 18 years of age.
  • Adults identified by a specialist to as having an immediate drug reaction that is likely related to an immunologically mediated reaction associated with a drug or externally administered substance.
  • Adults unable to provide informed consent and a decision maker/surrogate is not available.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Jacqueline Squire, M.D.

Open for enrollment

Contact information:

Meaghan Rodgers M.S., CCRP

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Alexei Gonzalez Estrada, M.D.

Open for enrollment

Contact information:

Jourdan Richardson

(480) 301-4226

Eau Claire, Wis.

Mayo Clinic principal investigator

Adela Taylor, M.D.

Open for enrollment

Contact information:

Adela Taylor M.D.

(715) 838-5321

More information


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