Thais de Azeredo Coutinho, M.D.

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• Aortic Function As A Predictor Of Thoracic Aortic Aneurysm (TAA) Expansion: Development And Validation Of A TAA Growth Prediction Model (PREDICT-TAA Study) Rochester, Minn.

  The purpose of this study is to develop and validate a prediction model for TAA growth that incorporates clinical, demographic and key aortic hemodynamic measures.

• Hemodynamic Effects Of Aldosterone Receptor Blockade In Degenerative Thoracic Aortic Aneurysm: A Pilot Randomized Controlled Trial (HEART: Pilot RCT) Rochester, Minn.

  The purpose of this study is to determine whether spironolactone reduces aortic stiffness, measured by carotid-femoral pulse wave velocity (cfPWV), compared with placebo, in patients with degenerative thoracic aortic aneurysms.

• The PROTECTA Study: Predicting Risk and Outcomes for Thoracic aortic aneurysm using Aortic Function Rochester, Minn.

  The purpose of this study is to identify key aortic parameters implicated in the development of adverse outcomes in TAA patients, in order to develop improved risk stratification and therapeutic strategies