Displaying 7 studies

  • A Study of Autoimmune Functions in Patients with Myocarditis Jacksonville, FL

    The purpose of this research is to study immune cells called T cells and monocytes (types of blood cells that fight infection and can also cause autoimmune disease) that may damage heart tissue during myocarditis (inflammation of the heart muscle). Cytokines (proteins that send signals between cells) found in the blood will be studied for their effects on blood immune cells to better understand how they can lead to heart failure during and after myocarditis.

  • Diagnosis and Treatment of Fulminant Myocarditis and Myopericarditis Rochester, MN

    If serum sST2 predicts heart failure (HF) in several cardiovascular disorders, in myocarditis patients.

  • Molecular Analysis of Blood for the Detection of Cardiovascular Pathogens Rochester, MN

    The purpose of this study is to test whether metagenomic shotgun sequencing can identify pathogens causing cardiovascular infections such as infective endocarditis or myocarditis.

  • 2-D Speckle Tracking in Diagnosis and Prognosis of Acute Myocarditis Rochester, MN

    In this study, we attempt to evaluate the LV and RV myocardial mechanical properties   in patients with myocarditis during the acute and convalescent phases.

  • A Study to Evaluate Inflammation of the Heart Muscle Tissue in Patients with Rheumatoid Arthritis Rochester, MN

    Rheumatoid arthritis (RA) patients have a higher prevalence of subclinical atherosclerosis than the general population. In addition, they experience higher rates of heart failure with preserved ejection fraction (HFpEF). There is evidence that myocardial mechanics and left ventricular diastolic function are more abnormal in the RA population and these changes occur earlier than in the general population. Recently a study suggested that RA patient have abnormal myocardial inflammation during a disease flare and that this is improved with anti-inflammatory treatment. Our study is aimed at describing the prevalence of myocardial inflammation in patients during active RA disease flares and comparing ...

  • A Study to Evaluate Depression, Anxiety, and Traumatic Stress in People with Myocarditis and Their Identified Supports Jacksonville, FL; Rochester, MN

    The purpose of this study is to validate measures of depression, anxiety, traumatic stress, and factors related to these outcomes in medical patients, to develop a model for identifying persons with myocarditis who are at risk for depressive and anxiety disorders (clinically significant depressive and anxious symptoms), and for examining the effects of anxiety and depression on quality of life and health outcomes in respondents with myocarditis and caregivers.

  • A Study to Investigate Outcomes and Management Effectiveness of Cardiogenic Shock II Patients Rochester, MN

    The purpose of this study is to develop a registry of patients with clinical cardiogenic shock (CS) in order to allow better definition of several key issues regarding cardiogenic shock.


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