-
Estradiol in the Immunopathology of MAC infection
Rochester, MN
The purpose of this study to assess the effect of estrogen on monocyte/macrophage response induced by MAC infection in vitro using murine peritoneal macrophages and human peripheral blood monocytes.
-
A Study To Evaluate Lamprene (Clofazimine) To Treat Non-Tuberculous Mycobacterial (NTM) Infections
Jacksonville, FL
The purpose of this study is to evaluate Lamprene (Clofazimine) to treat non-tuberculous mycobacterial (NTM) infections.
-
A Study To Compare Two Vs. Three Antibiotic Therapies For Pulmonary Mycobacterium Avium Complex Disease
Rochester, MN
The purpose of this study is to determine whether 2-drug therapy is non-inferior to 3-drug therapy against pulmonary mycobacterium avium complex (MAC) disease, and whether 2-drug therapy is better tolerated than 3-drug therapy.
-
A Study To Evaluate The Effectiveness And Safety Of An Amikacin Liposome Inhalation Suspension-based Regimen In Adults With Nontuberculous Mycobacterial Lung Infection
Jacksonville, FL; Rochester, MN
The purpose of this study is to evaluate the effectiveness of ALIS + azithromycin (AZI) + ethambutol (ETH) compared to the empty liposome control (ELC) + AZI + ETH on patient reported respiratory symptoms at Month 13.
-
A Study Of Inhaled Molgramostim In Cystic Fibrosis Subjects With Nontuberculous Mycobacterial (NTM) Infection
Rochester, MN
The purpose of this study is to evaluate the effectiveness of inhaled molgramostim, administered open-label, to adult cystic fibrosis subjects with chronic pulmonary nontuberculous mycobacterial (NTM) infection, with or without ongoing antimycobacterial guideline based combination therapy.