Clinical Trials

Incidence of anterior cruciate ligament (ACL) ruptures disproportionately affect female athletes at a rate 4-6 times greater than male counterparts. In addition, females have a reinjury rate 16 times that of healthy female controls and 4 times that of male ACL reconstruction (ACLR) counterparts. After ACL injury and throughout rehabilitation, a ubiquitous impairment that limits athlete progression to return to sport (RTS) is atrophy of the musculature surrounding the knee, termed arthrogenic muscle inhibition (AMI).The focus of the study is to develop an objective, reproducible, and reliable measure of neuromotor activation (directly correlated with AMI) and neuromuscular elicited muscle stiffness ...

We wish to examine pancreatic adenocarcinoma cell lines to determine what genes are being expressed in the cells that might cause muscle wasting in patients. We will also perform chemical analyses of plasma obtained from these patients to identify substances that might be causing muscle wasting. Finally, we will examine proteins that are secreted by such cells to identify mediator is of cachexia or muscle wasting.

The purpose of this study is to determine the long-term progression and outcomes in patients who have the diagnosis of Hirayama disease.