Clinical Trials

Multiple organ failure

Displaying 2 studies

A Study to Determine if an Early Alert Checklist Can Help Prevent Severe Organ Damage and Death in Patients with Acute Respiratory Failure Rochester, MN

Severe acute respiratory failure requiring prolonged mechanical ventilation is the most common form of acute organ dysfunction in the hospital, and is often associated with multiple organ failure, high mortality, and functional impairment. The purpose of this study is to improve the outcomes of patients at high risk with early intervention using an electronic medical records checklist aimed at preventing the lung injury that commonly leads to organ failure.
Evaluation Of The Efficacy And Safety Of Sarilumab In Hospitalized Patients With COVID-19 (Enrollment By Invitation Only) Rochester, MN

Phase 2: The primary objective of the study is to evaluate the clinical efficacy of sarilumab relative to the control arm in adult patients hospitalized with severe COVID-19.

Phase 3: The primary objective of the study is to evaluate the clinical efficacy of sarilumab relative to the control arm in adult patients hospitalized with severe or critical COVID-19.