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Impact Of Respiratory Muscle Training On Blood Glucose And Blood Pressure In Gestational Diabetes Mellitus
Rochester, MN
The purpose of this study is to evaluate the acute effects of a single session of RMT on blood glucose (BG) levels, BP and metabolic responses (e.g., oxygen consumption (VO2), heart rate (HR), tidal volume (Vt), respiratory exchange ratio (RER), respiratory rate (RR) and inspiratory pressure [IP]) in women diagnosed with GDM. Additionally, to examine the differential physiological responses across varying pressure resistance levels during RMT, and assess the feasibility and tolerability of the RMT in this population.
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A Study to Evaluate Proinsulin and Glucagon Secretion in Postpartum Women with and without Gestational Diabetes
Rochester, MN
The purpose of this study is to determine the changes in tissue function that occur in the first year postpartum in women with and without gestational diabetes mellitus.
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Mediators of insulin resistance in women with a history of gestational diabetes mellitus
Rochester, MN
Women with gestational diabetes mellitus (GDM) are likely to have insulin resistance that persists long after pregnancy, resulting in greater risk of developing type 2 diabetes mellitus (T2DM). The study will compare women with and without a previous diagnosis of GDM to determine if women with a history of GDM have abnormal fatty acid metabolism, specifically impaired adipose tissue lipolysis. The study will aim to determine whether women with a history of GDM have impaired pancreatic β-cell function. The study will determine whether women with a history of GDM have tissue specific defects in insulin action, and also identify the effect of a ...
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A Study to Evaluate the Effectiveness and Safety of Remdesivir to Treat Coronavirus Disease 2019 in an Outpatient Setting
Rochester, MN
The purpose of this study is to evaluate the effietiveness of remdesivir (RDV) in reducing the rate of of all-cause medically attended visits (MAVs; medical visits attended in person by the participant and a health care professional) or death in non-hospitalized participants with early stage coronavirus disease 2019 (COVID-19) and to evaluate the safety of RDV administered in an outpatient setting.