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Cell Biological Interrogation of Patient-derived Arteriovenous Malformation Cell Lines
Rochester, MN
The purpose of this study is to generate endothelial and smooth muscle cell lines from patients with brain arteriovenous malformations (AVM)s for subsequent use in cell culture (and eventually animal models) in order to delineate the underlying cell, molecular, genetic, and epigenetic features of brain AVMs.
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Treatment of Brain AVMs (TOBAS) Study
Jacksonville, FL
The purpose of this study is to offer the best management possible for patients with brain arteriovenous malformations (AVMs) (ruptured or unruptured) in terms of long-term outcomes, despite the presence of uncertainty.
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A Study to Assess Outcomes in Unruptured bAVM Patients
Rochester, MN
The purpose of this study is to identify robust, clinically-applicable risk factors for stroke and death in unruptured bAVMs, and study long-term outcomes in patients with and without treatment.
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Feasibility Study Comparing the Utility of GLOW800 and FL800 Intraoperative ICG-VA Tools for Intracranial Lesions
Scottsdale/Phoenix, AZ
The purpose of this study is to comparatively evaluate the use of the GLOW800 visualization tool for ICG-VA versus the standard of care visualization tool FL800.
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A Study to Assess if Using Holography/Augmented Reality and 3D-printed Models to Visualize Intracranial Diseases and Aid in Patient Education
Scottsdale/Phoenix, AZ
The purpose of this study is to assess if using holography/ Augmented Reality and 3D-printed models to visualize intracranial diseases and aid in patient education.
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A Study to Learn More About Intracranial Arteriovenous Malformation (AVM) in the Brain
Rochester, MN
The purpose of this study is to learn more about arteriovenous malformation (AVM), a type of blood vessel abnormality in the brain.
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Cerebrovascular Diseases Prospective Registry
Rochester, MN
The purpose of this study is for genetic analysis of specimens removed during cerebrovascular neurosurgery to better understand pathophysiology of cerebrovascular pathology.
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Intraventricular Nicardipine for Aneurysmal Subarachnoid Hemorrhage Related Vasospasm: Assessment on Clinical Outcomes of Stroke by 30 & 90 Days
Jacksonville, FL
The purpose is to study the effects of intraventricular nicardipine, a vasodilatory agent, on VP and secondary outcomes of stroke and functional outcome at 30 and 90 days compared to those not treated with this agent.
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Florida Cerebrovascular Disease Biorepository and Genomics Center
Jacksonville, FL
The aim of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida. The Center will collect and store detailed phenotypic information, DNA, and other biofluids on affected subjects with diverse cerebrovascular conditions, including, but not limited to, ischemic stroke, transient ischemic attack (TIA), intracerebral hemorrhage (ICH), aneurysmal subarachnoid hemorrhage (aSAH), vascular dementia (VAD), anoxic brain injury, unruptured intracranial aneurysm (UIA), cavernous malformation, arteriovenous malformations (AVM), carotid and vertebral arterial dissections, symptomatic and asymptomatic cervical carotid artery atherosclerotic stenosis, non-aneurysmal perimesencephalic subarachnoid hemorrhage (naSAH), cerebral venous thrombosis (CVT), moyamoya disease, fibrosmuscular dysplasia (FMD), non-traumatic, angiography-negative subarachnoid ...