A Study Of Non-invasive CVP Measurement Using Compression Ultrasonography

Overview

About this study

The purpose of this study is to evaluate whether the response of the IJ to extrinsic compression on two-dimensional ultrasound can serve as a non-invasive surrogate for invasive central venous pressure and to compare the response of the IJ to compression in patients with and without heart failure, fluid overload, and tricuspid regurgitation.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Patients referred to the cardiac catheterization laboratory for invasive right heart catheterization for hemodynamic assessment. We will include patients with normal or low EF, and across the spectrum of right heart function, volume status, and tricuspid regurgitation severity.

Exclusion Criteria:

Patient inability or unwillingness to undergo ultrasound assessment, or if ultrasound examination would, in the opinion of the investigator, somehow compromise the quality of data acquisition for the clinical case.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 03/24/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Barry Borlaug, M.D.	Contact us for the latest status

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Barry Borlaug, M.D.

Contact us for the latest status

More information

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