Barry A. Borlaug, M.D.

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SUMMARY

The research interests of Barry A. Borlaug, M.D., focus on the mechanisms, diagnosis and treatment of heart failure. Dr. Borlaug is particularly interested in heart failure with preserved ejection fraction. This type of heart failure occurs in about half of people with heart failure but has no proven treatment.

Dr. Borlaug leads clinical studies examining which factors contribute to functional limitations and symptoms of heart failure. He also examines treatment studies to identify new strategies, devices and treatments for patients with heart failure.

Focus areas

• Pathophysiology, diagnosis and treatment of heart failure with preserved ejection fraction.
• Mechanisms, characterization and treatment of pulmonary hypertension.
• Hemodynamics of heart failure, pericardial disease and valvular heart disease.
• Assessment of ventricular and vascular function.
• Cardiovascular aging and effects of obesity on cardiovascular function.

Significance to patient care

Dr. Borlaug studies how heart failure and pulmonary hypertension happen. He also studies the diagnosis and treatment of these conditions. Dr. Borlaug's research looks at why people with these diseases develop symptoms and disabilities that can lead to poor outcomes and a lower quality of life. Dr. Borlaug uses his findings to design and conduct clinical trials of new treatments. These treatments target the ways in which heart failure and pulmonary hypertension occur and cause issues. His goal is to improve health outcomes for people with these conditions.

Professional highlights

• Mayo Clinic:
  • William J. and Sharon A. Schoen Professor of Cardiology, 2025-present.
  • Distinguished Investigator Award, 2026.