Clinical Trials

Inclusion Criteria:

• Age ≥ 18 years

• Patients weighing >55 kilograms

• Admitted to ICU OR scheduled for cardiac or major non-cardiac surgeries/ACS-PCI with inpatient monitoring and anticipated stay ≥24 hours.

• Baseline GFR ≥15 ml/min/1.73 m²

• Able to provide informed consent themselves or their LAR (if they have no capacity).

• Adequate venous access for tracer injection

Exclusion Criteria:

• Patients with AKI at the time of enrollment

• Those on RRT (CRRT, IHD), or planned initiation of RRT within 24 hours of enrollment.

• Anuric patients

• Known allergy to Lumitrace or similar products.

• Severe skin conditions at the sensor site (extensive burns, tattoos, and adhesive allergy).

• Known pregnancy or lactation.

• Non-English speakers

• Prisoners and vulnerable adults

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 08/12/2026. Questions regarding updates should be directed to the study team contact.