A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection


About this study

The purpose of this research is to compare sympathetic function (flight or fight system), arterial structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age and sex matched control participants.

The sympathetic function across the menstrual cycle in premenopausal women with a history of SCAD will also be compared to age-matched premenopausal women. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Having spontaneous coronary artery dissection.
  • Sex and age-matched control subjects, 18 years of age and older.

Exclusion Criteria:

  • Individuals under 18 years of age.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Marysia Tweet, M.D., M.S.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Ischemic Heart Disease (IHD)

(507) 284-4256

More information


Publications are currently not available

Mayo Clinic Footer