A Study to Compare Circadian Phase in Patients with Wet Macular Degeneration to Controls Without Ocular Pathology


About this study

The purpose of this study is to determine if macular degeneration patients have a shift in their circadian rhythm due to pathology within the macula compared to patients without macular pathology. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults with wet macular degeneration by ophthalmology criteria

Exclusion Criteria:

  • Major depression on current therapy.
  • Severe mental illness or dementia.
  • Severe corneal opacities with difficulty in assessment of lens opacity or fundal examination.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Pablo Castillo, M.D.

Closed for enrollment

Contact information:

Pablo Castillo M.D.



More information


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