A Study to Assess Quality of Life with the PAH SYMPACT Questionnaire in the Pulmonary Hypertension Clinic

Overview

About this study

The primary purpose of this study is to administer the PAH SYMPACT questionnaire in 200 consecutive eligible patients attending the Mayo Clinic pulmonary hypertension clinic.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

Inclusion Criteria - All Cohorts:

  • Age 18 years old or above.
  • Consents to participate.

Inclusion Criteria - Group I PAH Cohort:

  • Documented group I PAH based upon these hemodynamic criteria: (mPAP > 20, PCW 18 or less, PVR > 3 Wood units.
  • Exclusion criteria for group I PAH:
    • Left sided heart disease (LVEF<50%, PAWP>18).

Inclusion Criteria - Group III PH Cohort:

  • Mean PAP > 20, PCW 18, PVR > 3 Wood units.
  • Parenchymal lung disease that in the opinion of the investigator qualifies patient as group III PH.

Inclusion Ccriteria - Group IV PH Cohort::

  • Documented chronic thromboembolic pulmonary hypertension or chronic thromboembolic disease with intent to treat with surgery, balloon pulmonary angioplasty, and/or PH medication.

Exclusion Criteria - All Groups:

  • Any other known concomitant life-threatening disease with a life expectancy <12 months.
  • Any other clinically relevant and/or serious chronic medical condition that would affect study participation in the opinion of the investigator.
  • Non English speaking.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Hilary DuBrock, M.D.

Open for enrollment

Contact information:

Louise Durst R.N.

(507)284-1838

durst.louise@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20455835

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