Detection of Circulating Biomarkers (Circulating Tumor Cells and Circulating Tumor DNA) in Patients with Head and Neck Carcinoma following Surgical Intervention


About this study

The goal of this research study is to evaluate the impact of surgical interventions on circulating biomarker dynamics and establish their prognostic role in carcinoma of the head and neck treated with intended curative surgery.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 18 years.
  • Diagnosed with cancer of the oral cavity, oropharynx, larynx or hypopharynx:
    • Any patient with lymphopathy;
    • Stage T2 cancer and above if no lymph node involvement.
  • Eligible for standard of care therapeutic surgical intervention in absence of neoadjuvant systemic therapy.

Exclusion Criteria:

  • Pregnant women.
  • Self-reported use of illicit drugs.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

David Lott, M.D.

Open for enrollment

Contact information:

Regina Becker

(480) 342-6079

More information


Publications are currently not available

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