A Study of Changes that Occur with Glaucoma Therapies and Provocative Tests


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 11-005011
    Sponsor Protocol Number: 11-005011

About this study

The purpose of this study is to understand the aqueous humor dynamics changes that occur with glaucoma therapies and provocative tests. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Both males and females will be included.
  • Patients with chronic disease (e.g. hypertension) will be included as long as their condition is stable, does not require treatment other than medications, and they are not using systemic steroids or medications known to affect aqueous humor flow rate (particularly beta-adrenergic blocking agents).
  • Patients with and without glaucoma will be included.

Exclusion Criteria:

  • Other specific exclusion criteria include trauma, narrow angles, uveitis, myopia greater than -4.00D, or hyperopia greater than +2.00D.
  • Pregnant or nursing women will not be included in the study.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Arthur Sit, M.D.

Closed for enrollment

Contact information:

JaMario Ayers




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