Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-004063
    NCT ID: NCT02951351
    Sponsor Protocol Number: 16-004063

About this study

The purpose of this study is to look at safety and patient comfort during eye injections. Specifically, it will look to see if an experience is improved with the use of 1 extra numbing drop.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Patients undergoing intravitreal injection who do not have active eye infections
  • Greater than 18 years of age

Exclusion Criteria:

  • Patients younger than 18 years of age
  • Patients with active eye infections

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jose Pulido, M.D.

Open for enrollment

Contact information:

Margaret Reynolds M.D.


Mayo Clinic Footer