Tai Chi on Colorectal Cancer Survivors With Fatigue


About this study

Age-adjusted colorectal cancer (CRC) mortality has declined over the past two decades for both genders leading to significant increase in the proportion of CRC survivors. Fatigue is one of the most consistently identified problems among CRC survivors, persisting a year or more after diagnosis for some. Physical activity is critical to improve fatigue symptoms among CRC survivors. It has been established in previous studies that CRC survivors who engage in physical exercise report reduced fatigue and better quality of life compared to those who lack physical exercise (Paddle, Au, & Courneya, 2008). However, it can be a challenge to engage fatigued CRC survivors in physical activity. An alternative form of physical exercise is Tai Chi Easy (TCEasy), a simple and repetitive form of exercise that consists of movements with meditation. When performed at a moderate level, TCEasy provides an alternative to standard moderate intensity aerobic exercise. Our Arizona State University collaborators in this proposed study have experience in testing the same form of exercise among women with breast cancer survivors. We intend to further study the effects of TCEasy in improving fatigue and fatigue related symptoms among the colorectal cancer survivors.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • 0.5 - 5 years following completion of treatment for CRC, or other types of cancer (breast, lung, ovarian)
  • Has neuropathy
  • Age 18 and up
  • Self-report of fatigue based on Fatigue Scale ( SF-36)score of ≤ 50

Exclusion Criteria:

  • Recurrence of CRC or other active cancer
  • Severe cachexia
  • Dizziness
  • Bone pain
  • Severe nausea (as judged by the investigator)
  • Uncontrolled diabetes
  • Untreated hypothyroidism
  • Practicing yoga, tai chi, qigong once a week or more
  • Hemoglobin < 9.0 g/dL
  • Unwilling to comply with scheduled visits and class participation, defined as attendance in 6 or more classes

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Donald Northfelt, M.D.

Closed for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office


More information


Publications are currently not available

Study Results Summary

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Supplemental Study Information

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