The Mayo Clinic Spontaneous Coronary Artery Dissection (SCAD) Research Program is part of an innovative multidisciplinary collaborative research and clinical practice initiative formed in 2010. The goal of the program is to advance the understanding of the underlying causes and risk factors for SCAD and develop solutions for optimal diagnosis, treatment and prevention.

The Mayo Clinic SCAD Research Program takes a novel approach to patient-initiated rare disease research, utilizing registries, comprehensive review of participant data, genetic analyses, advanced medical imaging and other collaborative studies. The research is based on a novel database registry and a DNA and plasma biobank. This approach, involving research colleagues from across Mayo and at select organizations, has already had an impact on the care of SCAD patients.