Core Services and Tools

The Genetics, Epigenetics and Biomarker Core of the Mayo Clinic Robert M. and Billie Kelley Pirnie Translational Polycystic Kidney Disease Center offers six main PKD services:

• Mayo PKD Clinical Database
• Mutation screening of cystic disease genes
• Cystic Kidney and Liver Disease Biobank
• Epigenetic analysis of human cystic disease
• Urine and serum collection and fractionation
• Distribution of full-length, tagged clones of PKD genes

Submitting samples

The core also accepts submissions of DNA.

• DNA submission criteria

Core tools

PKD research tools and resources include:

• Classification of Typical ADPKD Calculator
• Autosomal Dominant Polycystic Kidney Disease Mutation Database
• Ensembl genome browser
• The Human Gene Mutation Database
• Human Splicing Finder
• UCSC Genome Browser