Alzheimer's Disease and Related Dementias

Guojun Bu, Ph.D., leads a team of basic and clinical neuroscientists who work collaboratively to promote discovery and team-based science with an emphasis on translation. This work is defining the mechanisms to find cures for Alzheimer's disease and related dementias. The research team focuses on discovering new genes that modulate disease-related pathologies, synaptic functions and cognition, which defines how the genes contribute to disease processes. The team's research goal is to discover and validate new drug targets and therapeutic methods to treat these devastating yet complex diseases.