Alzheimer's Disease and Related Dementias

In the Mayo Clinic Discovery and Translation Labs, basic and clinical neuroscientists work collaboratively to promote discovery and team-based science with an emphasis on translation. This work is defining the mechanisms to find cures for Alzheimer's disease and related dementias. The research team focuses on discovering new genes that modulate disease-related pathologies, synaptic functions and cognition, which defines how the genes contribute to disease processes. The team's research goal is to discover and validate new drug targets and therapeutic methods to treat these devastating yet complex diseases.

Laboratories

• Comparative Pathogenesis of Alzheimer's Disease and Related Disorders: Casey N. Cook
• Dementia and Immunity: John D. Fryer
• Genetics of Alzheimer's Disease and Endophenotypes: Nilufer Ertekin-Taner
• Memory Disorders: Neill R. Graff-Radford
• Meningeal Lymphatics in Neurological Disorders: Sandro Da Mesquita
• Molecular Neurotherapeutics: Tsuneya Ikezu
• Neurobiology of Alzheimer's Disease and Related Dementias: Na Zhao
• Neurobiology of Neurodegenerative Diseases: Wilfried Rossoll
• Neurodegenerative Diseases: Leonard Petrucelli
• Neuropathology and Microscopy: Dennis W. Dickson
• Protein Biochemistry and Neuroenzymology: Terrone L. Rosenberry
• Translational Neuropathology: Melissa E. Murray

Faculty

• Minerva M. Carrasquillo, Ph.D.
• Casey N. Cook, Ph.D.
• Sandro Da Mesquita
• Pritam Das, Ph.D.
• Dennis W. Dickson, M.D.
• Nilufer Ertekin-Taner, M.D., Ph.D.
• John D. Fryer, Ph.D.
• Neill R. Graff-Radford, M.D.
• Seiko Ikezu, M.D.
• Tsuneya Ikezu, M.D., Ph.D.
• Takahisa Kanekiyo, M.D., Ph.D.
• Silvia S. Kang, Ph.D.
• Shunsuke Koga, M.D., Ph.D.
• Melissa E. Murray, Ph.D.
• Leonard Petrucelli, Ph.D.
• Rosa Rademakers, Ph.D.
• Terrone L. Rosenberry, Ph.D.
• Wilfried O. Rossoll, Ph.D.
• Steven G. Younkin, M.D., Ph.D.
• Jing Zhao, M.D., Ph.D.
• Na Zhao, M.D., Ph.D.