Biostatistics and Bioinformatics Core

    This is two combined images of hepatocellular carcinoma. The image on the right is a cancer cell map showing fluorescently labeled areas in blue, white, teal, green and pink, with 200 µm scale for reference. The image on the left shows a legend of the color-coded proteins, with DAPI in blue, keratin in white, vimentin in teal, E-cadherin in green and CD8 in pink.
    Hepatocellular carcinoma

    This figure showcases one of our active projects, where we apply Multiplexed Immunofluorescence (MxIF) and data-driven omics approaches to study hepatocellular carcinoma.

    The Biostatistics and Bioinformatics Core provides statistical, bioinformatics, computational biology collaboration, and data management support for Hepatobiliary SPORE research projects and cores.

    The core also provides data management for clinical trials, monitors adverse events and prepares data summaries for manuscript preparation. The Biostatistics and Bioinformatics Core works closely with the Hepatobiliary SPORE's other cores to ensure a smooth continuum of data flow for clinical trials.

    The Biostatistics and Bioinformatics Core:

    • Provides SPORE investigators access to expertise in collaborative development of study designs and analysis plans, state-of-the-art data analysis and interpretation, data management resources, sequencing alignment, variant calling, data analysis and quality assurance, pathway analysis, and access to and analysis of data in public databases.
    • Provides management and integration of existing and newly collected data through consistent and compatible data handling.
    • Supports the Biospecimen and Pathology Core by providing resources to the research community and a centralized system to facilitate collaboration and data reuse.

    Core leaders

    Head and shoulders photograph of Chen Wang, Ph.D.

    Chen Wang, Ph.D.
    Director, Bioinformatics

    Head and shoulders photograph of Qian Shi, Ph.D.

    Qian Shi, Ph.D.
    Director, Biostatistics

    Head and shoulders photograph of Zachary C. Fogarty

    Zachary C. Fogarty
    Staff Member, Bioinformatics

    Head and shoulders photograph of Erik Jessen, Ph.D.

    Erik Jessen, Ph.D.
    Staff Member, Bioinformatics

    Head and shoulders photograph of Chantal E. McCabe, Ph.D

    Chantal E. McCabe, Ph.D.
    Staff Member, Bioinformatics

    Head and shoulders photograph of Daniel R. O'Brien

    Daniel R. O'Brien
    Staff Member, Bioinformatics

    Head and shoulders photograph of Joseph J. Larson, M.S.

    Joseph J. Larson, M.S.
    Statistician

    Head and shoulders photograph of Paul J. Dizona, Ph.D.

    Paul J. Dizona, Ph.D.
    Statistical Programmer


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