Biostatistics and Bioinformatics Core

This figure showcases one of our active projects, where we apply Multiplexed Immunofluorescence (MxIF) and data-driven omics approaches to study hepatocellular carcinoma.
The Biostatistics and Bioinformatics Core provides statistical, bioinformatics, computational biology collaboration, and data management support for Hepatobiliary SPORE research projects and cores.
The core also provides data management for clinical trials, monitors adverse events and prepares data summaries for manuscript preparation. The Biostatistics and Bioinformatics Core works closely with the Hepatobiliary SPORE's other cores to ensure a smooth continuum of data flow for clinical trials.
The Biostatistics and Bioinformatics Core:
- Provides SPORE investigators access to expertise in collaborative development of study designs and analysis plans, state-of-the-art data analysis and interpretation, data management resources, sequencing alignment, variant calling, data analysis and quality assurance, pathway analysis, and access to and analysis of data in public databases.
- Provides management and integration of existing and newly collected data through consistent and compatible data handling.
- Supports the Biospecimen and Pathology Core by providing resources to the research community and a centralized system to facilitate collaboration and data reuse.
Core leaders

Chen Wang, Ph.D.
Director, Bioinformatics

Qian Shi, Ph.D.
Director, Biostatistics

Zachary C. Fogarty
Staff Member, Bioinformatics

Erik Jessen, Ph.D.
Staff Member, Bioinformatics

Chantal E. McCabe, Ph.D.
Staff Member, Bioinformatics

Daniel R. O'Brien
Staff Member, Bioinformatics

Joseph J. Larson, M.S.
Statistician

Paul J. Dizona, Ph.D.
Statistical Programmer
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