Publications

  1. Carlos AF, Tosakulwong N, Weigand SD, Boeve BF, Knopman DS, Petersen RC, Nguyen A, Reichard RR, Murray ME, Dickson DW, Josephs KA. Frequency and distribution of TAR DNA-binding protein 43 (TDP-43) pathology increase linearly with age in a large cohort of older adults with and without dementia. Acta Neuropathol. 2022 Jul; 144 (1):159-160 Epub 2022 May 10
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  2. Shir D, Graff-Radford J, Machulda MM, Pham NTT, Jack CR Jr, Lowe VJ, Whitwell JL, Josephs KA. Posterior cortical atrophy: Primary occipital variant. Eur J Neurol. 2022 Jul; 29 (7):2138-2143 Epub 2022 Mar 30
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  3. Murakami A, Koga S, Sekiya H, Oskarsson B, Boylan K, Petrucelli L, Josephs KA, Dickson DW. Old age amyotrophic lateral sclerosis and limbic TDP-43 pathology. Brain Pathol. 2022 Jun 17; e13100 Epub 2022 June 17
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  4. Carlos AF, Sekiya H, Koga S, Pham NTT, Ali F, Botha H, Clark HM, Coon EA, Lowe V, Ahlskog JE, Trejo-Lopez JA, Dickson DW, Whitwell JL, Josephs KA. Tau-PET and multimodal imaging in clinically atypical multiple system atrophy masquerading as progressive supranuclear palsy. Parkinsonism Relat Disord. 2022 Jun 16; 101:9-14 Epub 2022 June 16
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  5. Koga S, Josephs KA, Aiba I, Yoshida M, Dickson DW. Neuropathology and emerging biomarkers in corticobasal syndrome. J Neurol Neurosurg Psychiatry. 2022 Jun 13 Epub 2022 June 13
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  6. Singh NA, Tosakulwong N, Graff-Radford J, Machulda MM, Pham NTT, Sintini I, Weigand SD, Schwarz CG, Senjem ML, Carrasquillo MM, Ertekin-Taner N, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL. APOE epsilon4 influences medial temporal atrophy and tau deposition in atypical Alzheimer's disease. Alzheimers Dement. 2022 Jun 12 Epub 2022 June 12
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  7. Josephs KA, Tosakulwong N, Weigand SD, Buciuc M, Lowe VJ, Dickson DW, Whitwell JL. Relationship Between (18)F-Flortaucipir Uptake and Histologic Lesion Types in 4-Repeat Tauopathies. J Nucl Med. 2022 Jun; 63 (6):931-935 Epub 2021 Sept 23
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  8. Josephs KA, Weigand SD, Whitwell JL. Characterizing Amyloid-Positive Individuals With Normal Tau PET Levels After 5 Years: An ADNI Study. Neurology. 2022 May 31; 98 (22):e2282-e2292 Epub 2022 Mar 21
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  9. Gatto RG, Martin PR, Ali F, Clark HM, Duffy JR, Utianski RL, Botha H, Machulda MM, Dickson DW, Josephs KA, Whitwell JL. Diffusion tractography of superior cerebellar peduncle and dentatorubrothalamic tracts in two autopsy confirmed progressive supranuclear palsy variants: Richardson syndrome and the speech-language variant. Neuroimage Clin. 2022 May 11; 35:103030 [Epub ahead of print]
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  10. Polsinelli AJ, Machulda MM, Martin PR, Duffy JR, Clark HM, Butts AM, Botha H, Lowe VJ, Whitwell JL, Josephs KA, Utianski RL. Neuropsychological Profiles of Patients with Progressive Apraxia of Speech and Aphasia. J Int Neuropsychol Soc. 2022 May; 28 (5):441-451 Epub 2021 July 22
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  11. Whitwell J, Martin PR, Graff-Radford J, Machulda M, Sintini I, Buciuc M, Senjem ML, Schwarz CG, Botha H, Carrasquillo MM, Ertekin-Taner N, Lowe VJ, Jack CR, Josephs KA. Investigating Heterogeneity and Neuroanatomic Correlates of Longitudinal Clinical Decline in Atypical Alzheimer Disease. Neurology. 2022 Apr 28 [Epub ahead of print]
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  12. Grijalva RM, Pham NTT, Huang Q, Martin PR, Ali F, Clark HM, Duffy JR, Utianski RL, Botha H, Machulda MM, Weigand SD, Ahlskog JE, Dickson DW, Josephs KA, Whitwell JL. Brainstem Biomarkers of Clinical Variant and Pathology in Progressive Supranuclear Palsy. Mov Disord. 2022 Apr; 37 (4):702-712 Epub 2021 Dec 31
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  13. Carlos AF, Josephs KA. Frontotemporal lobar degeneration with TAR DNA-binding protein 43 (TDP-43): its journey of more than 100 years. J Neurol. 2022 Mar 23 [Epub ahead of print]
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  14. Utianski RL, Botha H, Caviness JN, Worrell GA, Duffy JR, Clark HM, Whitwell JL, Josephs KA. A Preliminary Report of Network Electroencephalographic Measures in Primary Progressive Apraxia of Speech and Aphasia. Brain Sci. 2022 Mar 12; 12 (3)
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  15. Hassan A, Mittal SO, Hu WT, Josephs KA, Sorenson EJ, Ahlskog JE. Does limited EMG denervation in early primary lateral sclerosis predict amyotrophic lateral sclerosis? Amyotroph Lateral Scler Frontotemporal Degener. 2022 Feb 16; 1-8. [Epub ahead of print]
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  16. Raghavan S, Przybelski SA, Reid RI, Lesnick TG, Ramanan VK, Botha H, Matchett BJ, Murray ME, Reichard RR, Knopman DS, Graff-Radford J, Jones DT, Lowe VJ, Mielke MM, Machulda MM, Petersen RC, Kantarci K, Whitwell JL, Josephs KA, Jack CR Jr, Vemuri P. White matter damage due to vascular, tau, and TDP-43 pathologies and its relevance to cognition. Acta Neuropathol Commun. 2022 Feb 5; 10 (1):16 Epub 2022 Feb 05
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  17. Koga S, Murakami A, Josephs KA, Dickson DW. Diffuse Lewy body disease presenting as Parkinson's disease with progressive aphasia. Neuropathology. 2022 Feb; 42 (1):82-89 Epub 2022 Jan 13
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  18. Bower SM, Weigand SD, Ali F, Clark HM, Botha H, Stierwalt JA, Whitwell JL, Josephs KA. Depression and Apathy across Different Variants of Progressive Supranuclear Palsy. Mov Disord Clin Pract. 2022 Feb; 9 (2):212-217 Epub 2021 Dec 31
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  19. Hokelekli FO, Duffy JR, Clark HM, Utianski RL, Botha H, Stierwalt JA, Strand EA, Machulda MM, Whitwell JL, Josephs KA. Cross-Sectional and Longitudinal Assessment of Behavior in Primary Progressive Apraxia of Speech and Agrammatic Aphasia. Dement Geriatr Cogn Disord. 2022; 51 (2):193-202 Epub 2022 May 06
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  20. Carlos AF, Tosakulwong N, Weigand SD, Buciuc M, Ali F, Clark HM, Botha H, Utianski RL, Machulda MM, Schwarz CG, Reid RI, Senjem ML, Jack CR Jr, Ahlskog JE, Dickson DW, Josephs KA, Whitwell JL. Histologic lesion type correlates of magnetic resonance imaging biomarkers in four-repeat tauopathies. Brain Commun. 2022; 4 (3):fcac108 Epub 2022 Apr 28
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  21. Buciuc M, Martin PR, Tosakulwong N, Murray ME, Petrucelli L, Senjem ML, Spychalla AJ, Knopman DS, Boeve BF, Petersen RC, Parisi JE, Reichard RR, Dickson DW, Jack CR Jr, Whitwell JL, Josephs KA. TDP-43-associated atrophy in brains with and without frontotemporal lobar degeneration. Neuroimage Clin. 2022; 34:102954 Epub 2022 Feb 04
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  22. Stang CD, Mullan AF, Camerucci E, Hajeb M, Turcano P, Martin P, Mielke MM, Josephs KA, Splett M, Abler V, Boeve BF, Bower JH, Savica R. Incidence, Prevalence, and Mortality of Psychosis Associated with Parkinson's Disease (1991-2010). J Parkinsons Dis. 2022; 12 (4):1319-1327
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  23. Valls Carbo A, Reid RI, Tosakulwong N, Weigand SD, Duffy JR, Clark HM, Utianski RL, Botha H, Machulda MM, Strand EA, Schwarz CG, Jack CR, Josephs KA, Whitwell JL. Tractography of supplementary motor area projections in progressive speech apraxia and aphasia. Neuroimage Clin. 2022; 34:102999 Epub 2022 Mar 30
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  24. Hokelekli FO, Duffy JR, Clark HM, Utianski RL, Botha H, Ali F, Stierwalt JA, Machulda MM, Reichard RR, Dickson DW, Whitwell JL, Josephs KA. Autopsy Validation of Progressive Supranuclear Palsy-Predominant Speech/Language Disorder Criteria. Mov Disord. 2022 Jan; 37 (1):213-218 Epub 2021 Oct 10
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  25. Josephs KA, Pham NTT, Graff-Radford J, Machulda MM, Lowe VJ, Whitwell JL. Medial Temporal Atrophy in Posterior Cortical Atrophy and Its Relationship to the Cingulate Island Sign. J Alzheimers Dis. 2022; 86 (1):491-498
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  26. Pottier C, Mateiu L, Baker MC, DeJesus-Hernandez M, Teixeira Vicente C, Finch NA, Tian S, van Blitterswijk M, Murray ME, Ren Y, Petrucelli L, Oskarsson B, Biernacka JM, Graff-Radford NR, Boeve BF, Petersen RC, Josephs KA, Asmann YW, Dickson DW, Rademakers R. Shared brain transcriptomic signature in TDP-43 type A FTLD patients with or without GRN mutations. Brain. 2021 Dec 16 [Epub ahead of print]
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  27. Chandregowda A, Clark HM, Duffy JR, Machulda MM, Lowe VJ, Whitwell JL, Josephs KA. Dynamic Aphasia as a Variant of Frontotemporal Dementia. Cogn Behav Neurol. 2021 Dec 2; 34 (4):303-318 Epub 2021 Dec 02
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  28. Dang J, Graff-Radford J, Duffy JR, Utianski RL, Clark HM, Stierwalt JA, Whitwell JL, Josephs KA, Botha H. Progressive apraxia of speech: delays to diagnosis and rates of alternative diagnoses. J Neurol. 2021 Dec; 268 (12):4752-4758 Epub 2021 May 04
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  29. Buciuc M, Whitwell JL, Baker MC, Rademakers R, Dickson DW, Josephs KA. Old age genetically confirmed frontotemporal lobar degeneration with TDP-43 has limbic predominant TDP-43 deposition. Neuropathol Appl Neurobiol. 2021 Dec; 47 (7):1050-1059 Epub 2021 May 21
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  30. Whitwell JL, Tosakulwong N, Weigand SD, Graff-Radford J, Ertekin-Taner N, Machulda MM, Duffy JR, Schwarz CG, Senjem ML, Jack CR, Lowe VJ, Josephs KA, Alzheimer's Disease Neuroimaging Initiative. Relationship of APOE, age at onset, amyloid and clinical phenotype in Alzheimer disease. Neurobiol Aging. 2021 Dec; 108:90-98 Epub 2021 Aug 25
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  31. Buciuc M, Josephs KA, Jones DT, Whitwell JL, Graff-Radford J. Progressive Auditory Verbal Agnosia Secondary to Alzheimer Disease. Neurology. 2021 Nov 9; 97 (19):908-909 Epub 2021 Sept 09
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  32. Utianski RL, Martin PR, Duffy JR, Botha H, Clark HM, Josephs KA. Assessing Change in Communication Limitations in Primary Progressive Apraxia of Speech and Aphasia: A 1-Year Follow-Up Study. Am J Speech Lang Pathol. 2021 Nov 4; 30 (6):2368-2378 Epub 2021 Sept 07
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  33. Scheffel L, Duffy JR, Strand EA, Josephs KA. Word Fluency Test Performance in Primary Progressive Aphasia and Primary Progressive Apraxia of Speech. Am J Speech Lang Pathol. 2021 Nov 4; 30 (6):2635-2642 Epub 2021 Oct 21
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  34. Clark HM, Tosakulwong N, Weigand SD, Ali F, Botha H, Pham NTT, Schwarz CG, Reid RI, Senjem ML, Jack CR Jr, Lowe VJ, Ahlskog JE, Josephs KA, Whitwell JL. Gray and White Matter Correlates of Dysphagia in Progressive Supranuclear Palsy. Mov Disord. 2021 Nov; 36 (11):2669-2675 Epub 2021 Aug 23
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  35. Ali F, Loushin SR, Botha H, Josephs KA, Whitwell JL, Kaufman K. Laboratory based assessment of gait and balance impairment in patients with progressive supranuclear palsy. J Neurol Sci. 2021 Oct 15; 429:118054 Epub 2021 Aug 25
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  36. Hokelekli FO, Ali F, Carlos AF, Martin PR, Clark HM, Duffy JR, Utianski RL, Botha H, St Louis EK, Whitwell JL, Josephs KA. Sleep disturbances in the speech-language variant of progressive supranuclear palsy. Parkinsonism Relat Disord. 2021 Oct; 91:9-12 Epub 2021 Aug 18
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  37. Whitwell JL, Tosakulwong N, Clark HM, Ali F, Botha H, Weigand SD, Sintini I, Machulda MM, Schwarz CG, Reid RI, Jack CR Jr, Ahlskog JE, Josephs KA. Diffusion tensor imaging analysis in three progressive supranuclear palsy variants. J Neurol. 2021 Sep; 268(9):3409-3420. Epub 2021 Mar 12.
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  38. Schwarz CG, Therneau TM, Weigand SD, Gunter JL, Lowe VJ, Przybelski SA, Senjem ML, Botha H, Vemuri P, Kantarci K, Boeve BF, Whitwell JL, Josephs KA, Petersen RC, Knopman DS, Jack CR Jr. Selecting software pipelines for change in flortaucipir SUVR: Balancing repeatability and group separation. Neuroimage. 2021 Sep; 238:118259 Epub 2021 June 09
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  39. Buciuc M, Duffy JR, Machulda MM, Graff-Radford J, Pham NTT, Martin PR, Senjem ML, Jack CR Jr, Ertekin-Taner N, Dickson DW, Lowe VJ, Whitwell JL, Josephs KA. Clinical, Imaging, and Pathologic Characteristics of Patients With Right vs Left Hemisphere-Predominant Logopenic Progressive Aphasia. Neurology. 2021 Aug 3; 97 (5):e523-e534 Epub 2021 June 04
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  40. Chandregowda A, Duffy JR, Machulda MM, Lowe VJ, Whitwell JL, Josephs KA. Neurodegeneration of the visual word form area in a patient with word form alexia. Neurol Clin Neurosci. 2021 Jul; 9 (4):359-360 Epub 2021 May 24
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  41. Clark HM, Utianski RL, Ali F, Botha H, Whitwell JL, Josephs KA. Motor Speech Disorders and Communication Limitations in Progressive Supranuclear Palsy. Am J Speech Lang Pathol. 2021 Jun 18; 30 (3S):1361-1372 Epub 2021 Mar 09
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  42. Josephs KA, Duffy JR, Clark HM, Utianski RL, Strand EA, Machulda MM, Botha H, Martin PR, Pham NTT, Stierwalt J, Ali F, Buciuc M, Baker M, Fernandez De Castro CH, Spychalla AJ, Schwarz CG, Reid RI, Senjem ML, Jack CR Jr, Lowe VJ, Bigio EH, Reichard RR, Polley EJ, Ertekin-Taner N, Rademakers R, DeTure MA, Ross OA, Dickson DW, Whitwell JL. A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech. Nat Commun. 2021 Jun 8; 12 (1):3452 Epub 2021 June 08
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  43. Whitwell JL, Martin P, Duffy JR, Clark HM, Utianski RL, Botha H, Machulda MM, Strand EA, Josephs KA. Survival Analysis in Primary Progressive Apraxia of Speech and Agrammatic Aphasia. Neurol Clin Pract. 2021 Jun; 11 (3):249-255
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  44. Petroi D, Walker GM, Duffy JR, Hickok GS, Josephs KA. A Cognitive Psychometric Investigation of Word Production and Phonological Error Rates in Logopenic Progressive Aphasia. Am J Speech Lang Pathol. 2021 May 18; 30 (3):1194-1202 Epub 2021 Apr 19
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  45. DeJesus-Hernandez M, Aleff RA, Jackson JL, Finch NA, Baker MC, Gendron TF, Murray ME, McLaughlin IJ, Harting JR, Graff-Radford NR, Oskarsson B, Knopman DS, Josephs KA, Boeve BF, Petersen RC, Fryer JD, Petrucelli L, Dickson DW, Rademakers R, Ebbert MTW, Wieben ED, van Blitterswijk M. Long-read targeted sequencing uncovers clinicopathological associations for C9orf72-linked diseases. Brain. 2021 May 7; 144 (4):1082-1088
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  46. Hassan A, Mittal SO, Hu WT, Josephs KA, Sorenson EJ, Ahlskog JE. Natural History of "Pure" Primary Lateral Sclerosis. Neurology. 2021 Apr 27; 96 (17):e2231-e2238 Epub 2021 Feb 26
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  47. Hokelekli FO, Whitwell JL, Machulda MM, Jones DT, Uitti RJ, Pham NTT, Giannini C, Baker M, Lowe VJ, Dickson DW, Josephs KA. Underlying pathology identified after 20 years of disease course in two cases of slowly progressive frontotemporal dementia syndromes. Neurocase. 2021 Apr; 27 (2):212-222 Epub 2021 Apr 27
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  48. Buciuc M, Whitwell JL, Kasanuki K, Graff-Radford J, Machulda MM, Duffy JR, Strand EA, Lowe VJ, Graff-Radford NR, Rush BK, Franczak MB, Flanagan ME, Baker MC, Rademakers R, Ross OA, Ghetti BF, Parisi JE, Raghunathan A, Reichard RR, Bigio EH, Dickson DW, Josephs KA. Lewy Body Disease is a Contributor to Logopenic Progressive Aphasia Phenotype. Ann Neurol. 2021 Mar; 89 (3):520-533 Epub 2020 Dec 17
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  49. Utianski RL, Martin PR, Hanley H, Duffy JR, Botha H, Clark HM, Whitwell JL, Josephs KA. A Longitudinal Evaluation of Speech Rate in Primary Progressive Apraxia of Speech. J Speech Lang Hear Res. 2021 Feb 17; 64 (2):392-404 Epub 2021 Jan 21
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  50. Sintini I, Graff-Radford J, Jones DT, Botha H, Martin PR, Machulda MM, Schwarz CG, Senjem ML, Gunter JL, Jack CR, Lowe VJ, Josephs KA, Whitwell JL. Tau and Amyloid Relationships with Resting-state Functional Connectivity in Atypical Alzheimer's Disease. Cereb Cortex. 2021 Feb 5; 31 (3):1693-1706
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  51. Utianski RL, Schwarz CG, Murray ME, Tranovich JF, Scott NE, Lowe VJ, Whitwell JL, Josephs KA. In Vivo Imaging and Autoradiography in a Case of Autopsy-Confirmed Pick Disease. Neurol Clin Pract. 2021 Feb; 11 (1):e11-e14
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  52. Buciuc M, Duffy JR, Machulda MM, Spychalla AJ, Gunter JL, Jack CR Jr, Giannini C, Raghunathan A, Dickson DW, Josephs KA, Whitwell JL. Association of amyloid angiopathy with microbleeds in logopenic progressive aphasia: an imaging-pathology study. Eur J Neurol. 2021 Feb; 28 (2):670-675 Epub 2020 Nov 12
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  53. Stang CD, Mullan AF, Hajeb M, Camerucci E, Turcano P, Martin P, Mielke MM, Josephs KA, Bower JH, St Louis EK, Boeve BF, Savica R. Timeline of Rapid Eye Movement Sleep Behavior Disorder in Overt Alpha-Synucleinopathies. Ann Neurol. 2021 Feb; 89 (2):293-303 Epub 2020 Nov 20
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  54. Curet Burleson AX, Pham NTT, Buciuc M, Botha H, Duffy JR, Clark HM, Utianski RL, Machulda MM, Baker MC, Rademakers R, Lowe VJ, Whitwell JL, Josephs KA. Neurobehavioral Characteristics of FDG-PET Defined Right-Dominant Semantic Dementia: A Longitudinal Study. Dement Geriatr Cogn Disord. 2021; 50 (1):17-28 Epub 2021 Mar 23
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  55. Buciuc M, Tosakulwong N, Machulda MM, Whitwell JL, Weigand SD, Murray ME, Reichard RR, Parisi JE, Dickson DW, Boeve BF, Knopman DS, Petersen RC, Josephs KA. TAR DNA-Binding Protein 43 Is Associated with Rate of Memory, Functional and Global Cognitive Decline in the Decade Prior to Death. J Alzheimers Dis. 2021; 80 (2):683-693
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  56. Coughlin DG, Dickson DW, Josephs KA, Litvan I. Progressive Supranuclear Palsy and Corticobasal Degeneration. Adv Exp Med Biol. 2021; 1281:151-176
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  57. Duffy JR, Utianski RL, Josephs KA. Primary Progressive Apraxia of Speech: From Recognition to Diagnosis and Care. Aphasiology. 2021; 35 (4):560-591 Epub 2020 July 07
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  58. Tetzloff KA, Duffy JR, Strand EA, Machulda MM, Schwarz CG, Senjem ML, Jack CR, Josephs KA, Whitwell JL. Phonological Errors in Posterior Cortical Atrophy. Dement Geriatr Cogn Disord. 2021; 50 (2):195-203 Epub 2021 July 16
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  59. Townley RA, Botha H, Graff-Radford J, Whitwell J, Boeve BF, Machulda MM, Fields JA, Drubach DA, Savica R, Petersen RC, Senjem ML, Knopman DS, Lowe VJ, Jack CR Jr, Josephs KA, Jones DT. Posterior cortical atrophy phenotypic heterogeneity revealed by decoding (18)F-FDG-PET. Brain Commun. 2021; 3 (4):fcab182 Epub 2021 Aug 19
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  60. Sintini I, Kaufman K, Botha H, Martin PR, Loushin SR, Senjem ML, Reid RI, Schwarz CG, Jack CR Jr, Lowe VJ, Josephs KA, Whitwell JL, Ali F. Neuroimaging correlates of gait abnormalities in progressive supranuclear palsy. Neuroimage Clin. 2021; 32:102850 Epub 2021 Oct 12
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  61. Whitwell JL, Tosakulwong N, Schwarz CC, Senjem ML, Spychalla AJ, Duffy JR, Graff-Radford J, Machulda MM, Boeve BF, Knopman DS, Petersen RC, Lowe VJ, Jack CR Jr, Dickson DW, Parisi JE, Josephs KA. Longitudinal anatomic, functional, and molecular characterization of Pick disease phenotypes. Neurology. 2020 Dec 15; 95 (24):e3190-e3202 Epub 2020 Sept 28
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  62. Josephs KA, Martin PR, Weigand SD, Tosakulwong N, Buciuc M, Murray ME, Petrucelli L, Senjem ML, Spychalla AJ, Knopman DS, Boeve BF, Petersen RC, Parisi JE, Dickson DW, Jack CR, Whitwell JL. Protein contributions to brain atrophy acceleration in Alzheimer's disease and primary age-related tauopathy. Brain. 2020 Dec 5; 143 (11):3463-3476
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  63. Seckin ZI, Duffy JR, Strand EA, Clark HM, Utianski RL, Machulda MM, Botha H, Ali F, Thu Pham NT, Lowe VJ, Whitwell JL, Josephs KA. The evolution of parkinsonism in primary progressive apraxia of speech: A 6-year longitudinal study. Parkinsonism Relat Disord. 2020 Dec; 81:34-40. Epub 2020 Oct 07.
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  64. Utianski RL, Clark HM, Duffy JR, Botha H, Whitwell JL, Josephs KA. Communication Limitations in Patients With Progressive Apraxia of Speech and Aphasia. Am J Speech Lang Pathol. 2020 Nov 12; 29 (4):1976-1986 Epub 2020 Aug 05
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  65. Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus JM, Shi J, Heckman MG, Spiegel MR, Cook C, Song Y, Yue M, Daughrity LM, Carlomagno Y, Jansen-West K, de Castro CF, DeTure M, Koga S, Wang YC, Sivakumar P, Bodo C, Candalija A, Talbot K, Selvaraj BT, Burr K, Chandran S, Newcombe J, Lashley T, Hubbard I, Catalano D, Kim D, Propp N, Fennessey S, Fagegaltier D, Phatnani H, Secrier M, Fisher EM, Oskarsson B, van Blitterswijk M, Rademakers R, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Josephs KA, Thompson EA, Raj T, Ward M, Dickson DW, Gendron TF, Fratta P, Petrucelli L, NYGC ALS Consortium. Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. J Clin Invest. 2020 Nov 2; 130 (11):6080-6092
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  66. Ghirelli A, Tosakulwong N, Weigand SD, Clark HM, Ali F, Botha H, Duffy JR, Utianski RL, Buciuc M, Murray ME, Labuzan SA, Spychalla AJ, Pham NTT, Schwarz CG, Senjem ML, Machulda MM, Baker M, Rademakers R, Filippi M, Jack CR Jr, Lowe VJ, Parisi JE, Dickson DW, Josephs KA, Whitwell JL. Sensitivity-Specificity of Tau and Amyloid beta Positron Emission Tomography in Frontotemporal Lobar Degeneration. Ann Neurol. 2020 Nov; 88 (5):1009-1022 Epub 2020 Sept 12
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  67. Boes S, Botha H, Machulda M, Lowe V, Graff-Radford J, Whitwell JL, Utianski RL, Duffy JR, Josephs KA. Dementia with Lewy bodies presenting as Logopenic variant primary progressive Aphasia. Neurocase. 2020 Oct; 26 (5):259-263 Epub 2020 July 16
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  68. Jack CR, Wiste HJ, Weigand SD, Therneau TM, Lowe VJ, Knopman DS, Botha H, Graff-Radford J, Jones DT, Ferman TJ, Boeve BF, Kantarci K, Vemuri P, Mielke MM, Whitwell J, Josephs K, Schwarz CG, Senjem ML, Gunter JL, Petersen RC. Predicting future rates of tau accumulation on PET. Brain. 2020 Oct 1; 143 (10):3136-3150
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  69. Seckin ZI, Whitwell JL, Utianski RL, Botha H, Ali F, Duffy JR, Clark HM, Machulda MM, Jordan LG, Min HK, Lowe VJ, Josephs KA. Ioflupane 123I (DAT scan) SPECT identifies dopamine receptor dysfunction early in the disease course in progressive apraxia of speech. J Neurol. 2020 Sep; 267 (9):2603-2611 Epub 2020 May 09
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  70. Choudhury P, Scharf EL, Paolini MA 2nd, Graff-Radford J, Alden EC, Machulda MM, Jones DT, Fields JA, Murray ME, Graff-Radford NR, Constantopoulos E, Reichard RR, Knopman DS, Duffy JR, Dickson DW, Parisi JE, Josephs KA, Petersen RC, Boeve BF. Pick's disease: clinicopathologic characterization of 21 cases. J Neurol. 2020 Sep; 267 (9):2697-2704 Epub 2020 May 21
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  71. Chen Z, Yan Yau W, Jaunmuktane Z, Tucci A, Sivakumar P, Gagliano Taliun SA, Turner C, Efthymiou S, Ibanez K, Sullivan R, Bibi F, Athanasiou-Fragkouli A, Bourinaris T, Zhang D, Revesz T, Lashley T, DeTure M, Dickson DW, Josephs KA, Gelpi E, Kovacs GG, Halliday G, Rowe DB, Blair I, Tienari PJ, Suomalainen A, Fox NC, Wood NW, Lees AJ, Haltia MJ, Hardy J, Ryten M, Vandrovcova J, Houlden H, Genomics England Research Consortium. Neuronal intranuclear inclusion disease is genetically heterogeneous. Ann Clin Transl Neurol. 2020 Sep; 7 (9):1716-1725 Epub 2020 Aug 10
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  72. Iankova V, Respondek G, Saranza G, Painous C, Camara A, Compta Y, Aiba I, Balint B, Giagkou N, Josephs KA, Otsuki M, Golbe LI, Bhatia KP, Stamelou M, Lang AE, Hoglinger GU, Movement Disorder Society-endorsed PSP Study Group. Video-tutorial for the Movement Disorder Society criteria for progressive supranuclear palsy. Parkinsonism Relat Disord. 2020 Sep; 78:200-203 Epub 2020 Sept 22
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  73. Clark HM, Stierwalt JAG, Tosakulwong N, Botha H, Ali F, Whitwell JL, Josephs KA. Dysphagia in Progressive Supranuclear Palsy. Dysphagia. 2020 Aug; 35 (4):667-676 Epub 2019 Nov 01
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  74. Buciuc M, Whitwell JL, Tosakulwong N, Weigand SD, Murray ME, Boeve BF, Knopman DS, Parisi JE, Petersen RC, Dickson DW, Josephs KA. Association between transactive response DNA-binding protein of 43 kDa type and cognitive resilience to Alzheimer's disease: a case-control study. Neurobiol Aging. 2020 Aug; 92:92-97 Epub 2020 Apr 15
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  75. Utianski RL, Botha H, Whitwell JL, Martin PR, Schwarz CG, Duffy JR, Clark HM, Spychalla AJ, Senjem ML, Petersen RC, Knopman DS, Jack CR Jr, Lowe VJ, Josephs KA. Longitudinal flortaucipir ([(18)F]AV-1451) PET uptake in semantic dementia. Neurobiol Aging. 2020 Aug; 92:135-140 Epub 2020 Apr 18
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  76. Buciuc M, Botha H, Murray ME, Schwarz CG, Senjem ML, Jones DT, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr, Petrucelli L, Parisi JE, Dickson DW, Lowe V, Whitwell JL, Josephs KA. Utility of FDG-PET in diagnosis of Alzheimer-related TDP-43 proteinopathy. Neurology. 2020 Jul 7; 95 (1):e23-e34 Epub 2020 June 09
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  293. Mateen FJ, Josephs KA, Parisi JE, Drubach DA, Caselli RJ, Kantarci K, Jack C Jr, Boeve BF. Steroid-responsive encephalopathy subsequently associated with Alzheimer's disease pathology: a case series. Neurocase. 2012 Feb; 18: (1)1-12.
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  294. Whitwell JL, Josephs KA. Neuroimaging in frontotemporal lobar degeneration--predicting molecular pathology. Nat Rev Neurol. 2012 Jan 31; 8 (3):131-42
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  296. Graff-Radford J, Whitwell JL, Geda YE, Josephs KA. Clinical and imaging features of Othello's syndrome. Eur J Neurol. 2012 Jan; 19 (1):38-46 Epub 2011 Apr 25
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  297. Coon EA, Whitwell JL, Parisi JE, Dickson DW, Josephs KA. Right temporal variant frontotemporal dementia with motor neuron disease. J Clin Neurosci. 2012 Jan; 19 (1):85-91 Epub 2011 Nov 02
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  298. Hassan A, Parisi JE, Josephs KA. Autopsy-proven progressive supranuclear palsy presenting as behavioral variant frontotemporal dementia. Neurocase. 2012; 18 (6):478-88 Epub 2011 Dec 20
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  299. Murray ME, DeJesus-Hernandez M, Rutherford NJ, Baker M, Duara R, Graff-Radford NR, Wszolek ZK, Ferman TJ, Josephs KA, Boylan KB, Rademakers R, Dickson DW. Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72. Acta Neuropathol. 2011 Dec; 122 (6):673-90 Epub 2011 Nov 15
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  300. Graff-Radford J, Whitwell JL, Trenerry MR, Ahlskog JE, Jensen MD, Jack CR Jr, Josephs KA. Focal brain atrophy in gastric bypass patients with cognitive complaints. J Clin Neurosci. 2011 Dec; 18 (12):1671-6 Epub 2011 Nov 15
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  301. Dickson DW, Kouri N, Murray ME, Josephs KA. Neuropathology of frontotemporal lobar degeneration-tau (FTLD-tau). J Mol Neurosci. 2011 Nov; 45 (3):384-9 Epub 2011 July 01
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  302. Whitwell JL, Jack CR Jr, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Josephs KA. Imaging signatures of molecular pathology in behavioral variant frontotemporal dementia. J Mol Neurosci. 2011 Nov; 45 (3):372-8 Epub 2011 May 10
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  303. Hassan A, Whitwell JL, Josephs KA. The corticobasal syndrome-Alzheimer's disease conundrum. Expert Rev Neurother. 2011 Nov; 11 (11):1569-78
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  304. Kouri N, Murray ME, Hassan A, Rademakers R, Uitti RJ, Boeve BF, Graff-Radford NR, Wszolek ZK, Litvan I, Josephs KA, Dickson DW. Neuropathological features of corticobasal degeneration presenting as corticobasal syndrome or Richardson syndrome. Brain. 2011 Nov; 134 (Pt 11):3264-75 Epub 2011 Sept 20
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  305. Kocerha J, Kouri N, Baker M, Finch N, DeJesus-Hernandez M, Gonzalez J, Chidamparam K, Josephs KA, Boeve BF, Graff-Radford NR, Crook J, Dickson DW, Rademakers R. Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations. BMC Genomics. 2011 Oct 27; 12:527
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  307. Mateen FJ, Josephs KA, Trenerry MR, Felmlee-Devine MD, Weaver AL, Carone M, White RD. Long-term cognitive outcomes following out-of-hospital cardiac arrest: a population-based study. Neurology. 2011 Oct 11; 77(15):1438-45. Epub 2011 Sep 14.
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  308. Whitwell JL, Jack CR Jr, Przybelski SA, Parisi JE, Senjem ML, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Josephs KA. Temporoparietal atrophy: a marker of AD pathology independent of clinical diagnosis. Neurobiol Aging. 2011 Sep; 32 (9):1531-41 Epub 2009 Nov 14
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  309. Savica R, Rabinstein AA, Josephs KA. Ifosfamide associated myoclonus-encephalopathy syndrome. J Neurol. 2011 Sep; 258 (9):1729-31 Epub 2011 Mar 12
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  310. Whitwell JL, Avula R, Master A, Vemuri P, Senjem ML, Jones DT, Jack CR Jr, Josephs KA. Disrupted thalamocortical connectivity in PSP: a resting-state fMRI, DTI, and VBM study. Parkinsonism Relat Disord. 2011 Sep; 17 (8):599-605 Epub 2011 June 12
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  311. Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EG, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno-Tempini ML, Rosen H, Prioleau-Latham CE, Lee A, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor MN, Warren JD, Fox NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Grossman M, Miller BL. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain. 2011 Sep; 134(Pt 9):2456-77. Epub 2011 Aug 02.
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  312. Whitwell JL, Josephs KA, Avula R, Tosakulwong N, Weigand SD, Senjem ML, Vemuri P, Jones DT, Gunter JL, Baker M, Wszolek ZK, Knopman DS, Rademakers R, Petersen RC, Boeve BF, Jack CR Jr. Altered functional connectivity in asymptomatic MAPT subjects: a comparison to bvFTD. Neurology. 2011 Aug 30; 77 (9):866-74 Epub 2011 Aug 17
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  313. Josephs KA, Hodges JR, Snowden JS, Mackenzie IR, Neumann M, Mann DM, Dickson DW. Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathol. 2011 Aug; 122 (2):137-53 Epub 2011 May 26
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  314. Savica R, Matsumoto JY, Josephs KA, Ahlskog JE, Stead M, Lee KH, Klassen BT. Deep brain stimulation in benign tremulous parkinsonism. Arch Neurol. 2011 Aug; 68 (8):1033-6
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  315. Whitwell JL, Weigand SD, Gunter JL, Boeve BF, Rademakers R, Baker M, Knopman DS, Wszolek ZK, Petersen RC, Jack CR Jr, Josephs KA. Trajectories of brain and hippocampal atrophy in FTD with mutations in MAPT or GRN. Neurology. 2011 Jul 26; 77 (4):393-8 Epub 2011 July 13
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  316. Cornelius JR, Pittock SJ, McKeon A, Lennon VA, Aston PA, Josephs KA, Tippmann-Peikert M, Silber MH. Sleep manifestations of voltage-gated potassium channel complex autoimmunity. Arch Neurol. 2011 Jun; 68 (6):733-8
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  317. Whitwell JL, Master AV, Avula R, Kantarci K, Eggers SD, Edmonson HA, Jack CR Jr, Josephs KA. Clinical correlates of white matter tract degeneration in progressive supranuclear palsy. Arch Neurol. 2011 Jun; 68 (6):753-60
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  318. Coon EA, Sorenson EJ, Whitwell JL, Knopman DS, Josephs KA. Predicting survival in frontotemporal dementia with motor neuron disease. Neurology. 2011 May 31; 76 (22):1886-93
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  319. Frigerio R, Fujishiro H, Ahn TB, Josephs KA, Maraganore DM, DelleDonne A, Parisi JE, Klos KJ, Boeve BF, Dickson DW, Ahlskog JE. Incidental Lewy body disease: do some cases represent a preclinical stage of dementia with Lewy bodies? Neurobiol Aging. 2011 May; 32 (5):857-63 Epub 2009 June 26
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  320. Kouri N, Whitwell JL, Josephs KA, Rademakers R, Dickson DW. Corticobasal degeneration: a pathologically distinct 4R tauopathy. Nat Rev Neurol. 2011 May; 7 (5):263-72 Epub 2011 Apr 12
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  321. Li X, Lapid MI, Burton MC, Josephs KA. Psychoses as the presenting manifestation of Creutzfeldt-Jakob disease in an elderly male. Gen Hosp Psychiatry. 2011 May-Jun; 33(3):302.e7-9. Epub 2011 Mar 24.
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  322. Hassan A, Bower JH, Kumar N, Matsumoto JY, Fealey RD, Josephs KA, Ahlskog JE. Dopamine agonist-triggered pathological behaviors: surveillance in the PD clinic reveals high frequencies. Parkinsonism Relat Disord. 2011 May; 17 (4):260-4 Epub 2011 Feb 09
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  323. Wicklund MR, Mokri B, Drubach DA, Boeve BF, Parisi JE, Josephs KA. Frontotemporal brain sagging syndrome: an SIH-like presentation mimicking FTD. Neurology. 2011 Apr 19; 76 (16):1377-82
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  324. Vemuri P, Simon G, Kantarci K, Whitwell JL, Senjem ML, Przybelski SA, Gunter JL, Josephs KA, Knopman DS, Boeve BF, Ferman TJ, Dickson DW, Parisi JE, Petersen RC, Jack CR Jr. Antemortem differential diagnosis of dementia pathology using structural MRI: Differential-STAND. Neuroimage. 2011 Mar 15; 55 (2):522-31 Epub 2010 Dec 31
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  325. Passov V, Gavrilova RH, Strand E, Cerhan JH, Josephs KA. Sporadic corticobasal syndrome with progranulin mutation presenting as progressive apraxic agraphia. Arch Neurol. 2011 Mar; 68 (3):376-80
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  326. Claassen DO, Lowe VJ, Peller PJ, Petersen RC, Josephs KA. Amyloid and glucose imaging in dementia with Lewy bodies and multiple systems atrophy. Parkinsonism Relat Disord. 2011 Mar; 17(3):160-5. Epub 2010 Dec 31.
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  327. Josephs KA, Whitwell JL, Eggers SD, Senjem ML, Jack CR Jr. Gray matter correlates of behavioral severity in progressive supranuclear palsy. Mov Disord. 2011 Feb 15; 26(3):493-8. Epub 2011 Jan 12.
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  328. Josephs KA Jr, Whitwell JL, Weigand SD, Senjem ML, Boeve BF, Knopman DS, Smith GE, Ivnik RJ, Jack CR Jr, Petersen RC. Predicting functional decline in behavioural variant frontotemporal dementia. Brain. 2011 Feb; 134 (Pt 2):432-48 Epub 2011 Jan 20
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  330. Hassan A, Bower JH, Kumar N, Matsumoto JY, Fealey RD, Josephs KA, Ahlskog JE. Corrigendum to "Dopamine agonist-triggered pathological behaviors: Surveillance in the PD clinic reveals high frequencies" [Parkinsonism Relat Disord 17 (2011) 260-264]. Parkinsonism Relat Disord. 2011; 17(6):499.
  331. Whitwell JL, Jack CR Jr, Parisi JE, Senjem ML, Knopman DS, Boeve BF, Rademakers R, Baker M, Petersen RC, Dickson DW, Josephs KA. Does TDP-43 type confer a distinct pattern of atrophy in frontotemporal lobar degeneration? Neurology. 2010 Dec 14; 75 (24):2212-20
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  332. Graff-Radford J, Ahlskog JE, Bower JH, Josephs KA. Dopamine agonists and Othello's syndrome. Parkinsonism Relat Disord. 2010 Dec; 16 (10):680-2 Epub 2010 Sept 09
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  333. Whitwell JL, Jack CR Jr, Boeve BF, Parisi JE, Ahlskog JE, Drubach DA, Senjem ML, Knopman DS, Petersen RC, Dickson DW, Josephs KA. Imaging correlates of pathology in corticobasal syndrome. Neurology. 2010 Nov 23; 75 (21):1879-87
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  334. Flanagan EP, McKeon A, Lennon VA, Boeve BF, Trenerry MR, Tan KM, Drubach DA, Josephs KA, Britton JW, Mandrekar JN, Lowe V, Parisi JE, Pittock SJ. Autoimmune dementia: clinical course and predictors of immunotherapy response. Mayo Clin Proc. 2010 Oct; 85 (10):881-97
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  335. Josephs KA. Dementia and the TAR DNA binding protein 43. Clin Pharmacol Ther. 2010 Oct; 88: (4)555-8.
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  336. Claassen DO, Josephs KA, Ahlskog JE, Silber MH, Tippmann-Peikert M, Boeve BF. REM sleep behavior disorder preceding other aspects of synucleinopathies by up to half a century. Neurology. 2010 Aug 10; 75 (6):494-9 Epub 2010 July 28
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  337. Dickson DW, Ahmed Z, Algom AA, Tsuboi Y, Josephs KA. Neuropathology of variants of progressive supranuclear palsy. Curr Opin Neurol. 2010 Aug; 23 (4):394-400
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  338. Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Petersen RC, Hu WT, Parisi JE, Dickson DW, Jack CR Jr. Anatomical differences between CBS-corticobasal degeneration and CBS-Alzheimer's disease. Mov Disord. 2010 Jul 15; 25 (9):1246-52
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  339. Josephs KA, Whitwell JL, Parisi JE, Petersen RC, Boeve BF, Jack CR Jr, Dickson DW. Caudate atrophy on MRI is a characteristic feature of FTLD-FUS. Eur J Neurol. 2010 Jul; 17 (7):969-75 Epub 2010 Mar 03
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  340. Urwin H, Josephs KA, Rohrer JD, Mackenzie IR, Neumann M, Authier A, Seelaar H, Van Swieten JC, Brown JM, Johannsen P, Nielsen JE, Holm IE, FReJA Consortium, Dickson DW, Rademakers R, Graff-Radford NR, Parisi JE, Petersen RC, Hatanpaa KJ, White CL 3rd, Weiner MF, Geser F, Van Deerlin VM, Trojanowski JQ, Miller BL, Seeley WW, van der Zee J, Kumar-Singh S, Engelborghs S, De Deyn PP, Van Broeckhoven C, Bigio EH, Deng HX, Halliday GM, Kril JJ, Munoz DG, Mann DM, Pickering-Brown SM, Doodeman V, Adamson G, Ghazi-Noori S, Fisher EM, Holton JL, Revesz T, Rossor MN, Collinge J, Mead S, Isaacs AM. FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. Acta Neuropathol. 2010 Jul; 120(1):33-41. Epub 2010 May 20.
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  341. Josephs KA, Duffy JR, Fossett TR, Strand EA, Claassen DO, Whitwell JL, Peller PJ. Fluorodeoxyglucose F18 positron emission tomography in progressive apraxia of speech and primary progressive aphasia variants. Arch Neurol. 2010 May; 67: (5)596-605.
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  342. Whitwell JL, Avula R, Senjem ML, Kantarci K, Weigand SD, Samikoglu A, Edmonson HA, Vemuri P, Knopman DS, Boeve BF, Petersen RC, Josephs KA, Jack CR Jr. Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia. Neurology. 2010 Apr 20; 74 (16):1279-87
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  343. Gendron TF, Josephs KA, Petrucelli L. Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration. Neuropathol Appl Neurobiol. 2010 Apr; 36 (2):97-112 Epub 2010 Feb 19
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  344. Hassan A, Whitwell JL, Boeve BF, Jack CR Jr, Parisi JE, Dickson DW, Josephs KA. Symmetric corticobasal degeneration (S-CBD). Parkinsonism Relat Disord. 2010 Mar; 16 (3):208-14 Epub 2009 Dec 16
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  345. Claassen DO, Josephs KA, Peller PJ. The stripe of primary lateral sclerosis: focal primary motor cortex hypometabolism seen on fluorodeoxyglucose F18 positron emission tomography. Arch Neurol. 2010 Jan; 67: (1)122-5.
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  346. Dickson DW, Fujishiro H, Orr C, DelleDonne A, Josephs KA, Frigerio R, Burnett M, Parisi JE, Klos KJ, Ahlskog JE. Neuropathology of non-motor features of Parkinson disease. Parkinsonism Relat Disord. 2009 Dec; 15 Suppl 3:S1-5
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  347. Josephs KA, Whitwell JL, Knopman DS, Boeve BF, Vemuri P, Senjem ML, Parisi JE, Ivnik RJ, Dickson DW, Petersen RC, Jack CR Jr. Two distinct subtypes of right temporal variant frontotemporal dementia. Neurology. 2009 Nov 3; 73 (18):1443-50
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  348. Whitwell JL, Przybelski SA, Weigand SD, Ivnik RJ, Vemuri P, Gunter JL, Senjem ML, Shiung MM, Boeve BF, Knopman DS, Parisi JE, Dickson DW, Petersen RC, Jack CR Jr, Josephs KA. Distinct anatomical subtypes of the behavioural variant of frontotemporal dementia: a cluster analysis study. Brain. 2009 Nov; 132 (Pt 11):2932-46 Epub 2009 Sept 17
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  349. Hu WT, Seelaar H, Josephs KA, Knopman DS, Boeve BF, Sorenson EJ, McCluskey L, Elman L, Schelhaas HJ, Parisi JE, Kuesters B, Lee VM, Trojanowski JQ, Petersen RC, van Swieten JC, Grossman M. Survival profiles of patients with frontotemporal dementia and motor neuron disease. Arch Neurol. 2009 Nov; 66 (11):1359-64
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  350. Cobb SA, Wider C, Ross OA, Mata IF, Adler CH, Rajput A, Rajput AH, Wu RM, Hauser R, Josephs KA, Carr J, Gwinn K, Heckman MG, Aasly JO, Lynch T, Uitti RJ, Wszolek ZK, Kapatos G, Farrer MJ. GCH1 in darly-onset Parkinson's disease. Mov Disord. 2009 Oct 30; 24(14):2070-5.
  351. Cobb SA, Wider C, Ross OA, Mata IF, Adler CH, Rajput A, Rajput AH, Wu RM, Hauser R, Josephs KA, Carr J, Gwinn K, Heckman MG, Aasly JO, Lynch T, Uitti RJ, Wszolek ZK, Kapatos G, Farrer MJ. GCH1 in early-onset Parkinson's disease. Mov Disord. 2009 Oct 30; 24 (14):2070-5
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  352. Whitwell JL, Jack CR Jr, Boeve BF, Senjem ML, Baker M, Ivnik RJ, Knopman DS, Wszolek ZK, Petersen RC, Rademakers R, Josephs KA. Atrophy patterns in IVS10+16, IVS10+3, N279K, S305N, P301L, and V337M MAPT mutations. Neurology. 2009 Sep 29; 73 (13):1058-65
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  353. Josephs KA, Stroh A, Dugger B, Dickson DW. Evaluation of subcortical pathology and clinical correlations in FTLD-U subtypes. Acta Neuropathol. 2009 Sep; 118 (3):349-58 Epub 2009 May 20
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  354. Frigerio R, Fujishiro H, Maraganore DM, Klos KJ, DelleDonne A, Heckman MG, Crook JE, Josephs KA, Parisi JE, Boeve BF, Dickson DW, Ahlskog JE. Comparison of risk factor profiles in incidental Lewy body disease and Parkinson disease. Arch Neurol. 2009 Sep; 66 (9):1114-9
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  355. Hu WT, Rippon GW, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Josephs KA. Alzheimer's disease and corticobasal degeneration presenting as corticobasal syndrome. Mov Disord. 2009 Jul 15; 24 (9):1375-9
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  356. Mateen FJ, Josephs KA. The clinical spectrum of stereotypies in frontotemporal lobar degeneration. Mov Disord. 2009 Jun 15; 24 (8):1237-40
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  357. Vilarino-Guell C, Wider C, Soto-Ortolaza AI, Cobb SA, Kachergus JM, Keeling BH, Dachsel JC, Hulihan MM, Dickson DW, Wszolek ZK, Uitti RJ, Graff-Radford NR, Boeve BF, Josephs KA, Miller B, Boylan KB, Gwinn K, Adler CH, Aasly JO, Hentati F, Destee A, Krygowska-Wajs A, Chartier-Harlin MC, Ross OA, Rademakers R, Farrer MJ. Characterization of DCTN1 genetic variability in neurodegeneration. Neurology. 2009 Jun 9; 72 (23):2024-8
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  358. Kelley BJ, Haidar W, Boeve BF, Baker M, Graff-Radford NR, Krefft T, Frank AR, Jack CR Jr, Shiung M, Knopman DS, Josephs KA, Parashos SA, Rademakers R, Hutton M, Pickering-Brown S, Adamson J, Kuntz KM, Dickson DW, Parisi JE, Smith GE, Ivnik RJ, Petersen RC. Prominent phenotypic variability associated with mutations in Progranulin. Neurobiol Aging. 2009 May; 30 (5):739-51 Epub 2007 Oct 18
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  360. Kelley BJ, Boeve BF, Josephs KA. Rapidly progressive young-onset dementia. Cogn Behav Neurol. 2009 Mar; 22 (1):22-7
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  361. Josephs KA, Ahlskog JE, Parisi JE, Boeve BF, Crum BA, Giannini C, Petersen RC. Rapidly progressive neurodegenerative dementias. Arch Neurol. 2009 Feb; 66 (2):201-7
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  362. McKeon A, Ahlskog JE, Bower JH, Josephs KA, Matsumoto JY. Psychogenic tremor: long-term prognosis in patients with electrophysiologically confirmed disease. Mov Disord. 2009 Jan 15; 24(1):72-6.
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  363. Whitwell JL, Jack CR Jr, Senjem ML, Parisi JE, Boeve BF, Knopman DS, Dickson DW, Petersen RC, Josephs KA. MRI correlates of protein deposition and disease severity in postmortem frontotemporal lobar degeneration. Neurodegener Dis. 2009; 6 (3):106-17 Epub 2009 Mar 19
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  364. Kelley BJ, Boeve BF, Josephs KA. Cognitive and noncognitive neurological features of young-onset dementia. Dement Geriatr Cogn Disord. 2009; 27 (6):564-71 Epub 2009 July 11
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  365. Cooper AD, Josephs KA. Photophobia, visual hallucinations, and REM sleep behavior disorder in progressive supranuclear palsy and corticobasal degeneration: a prospective study. Parkinsonism Relat Disord. 2009 Jan; 15(1):59-61. Epub 2008 Mar 06.
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  366. Yurchenko A, Lapid MI, Josephs KA. Frontotemporal dementia in older adults: Diagnostic and therapeutic challenges. Clinical Geriatrics. 2009; 17(1):26-31.
  367. Whitwell JL, Josephs KA. Imaging in familial frontotemporal lobar degeneration with mutations in MAPT or PGRN. European Neurological Journal. 2009; 1:25-31.
  368. Czarnecki K, Duffy JR, Nehl CR, Cross SA, Molano JR, Jack CR Jr, Shiung MM, Josephs KA, Boeve BF. Very early semantic dementia with progressive temporal lobe atrophy: an 8-year longitudinal study. Arch Neurol. 2008 Dec; 65 (12):1659-63
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  369. Rademakers R, Eriksen JL, Baker M, Robinson T, Ahmed Z, Lincoln SJ, Finch N, Rutherford NJ, Crook RJ, Josephs KA, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Caselli RJ, Wszolek ZK, Uitti RJ, Feldman H, Hutton ML, Mackenzie IR, Graff-Radford NR, Dickson DW. Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia. Hum Mol Genet. 2008 Dec 1; 17 (23):3631-42 Epub 2008 Aug 21
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  370. Josephs KA, Whitwell JL, Jack CR Jr. Anatomic correlates of stereotypies in frontotemporal lobar degeneration. Neurobiol Aging. 2008 Dec; 29 (12):1859-63 Epub 2007 June 14
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  371. Josephs KA, Duffy JR. Apraxia of speech and nonfluent aphasia: a new clinical marker for corticobasal degeneration and progressive supranuclear palsy. Curr Opin Neurol. 2008 Dec; 21 (6):688-92
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  372. Josephs KA, Whitwell JL, Vemuri P, Senjem ML, Boeve BF, Knopman DS, Smith GE, Ivnik RJ, Petersen RC, Jack CR Jr. The anatomic correlate of prosopagnosia in semantic dementia. Neurology. 2008 Nov 11; 71 (20):1628-33
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  373. Kelley BJ, Boeve BF, Josephs KA. Young-onset dementia: demographic and etiologic characteristics of 235 patients. Arch Neurol. 2008 Nov; 65 (11):1502-8
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  374. Whitwell JL, Josephs KA, Murray ME, Kantarci K, Przybelski SA, Weigand SD, Vemuri P, Senjem ML, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Jack CR Jr. MRI correlates of neurofibrillary tangle pathology at autopsy: a voxel-based morphometry study. Neurology. 2008 Sep 2; 71 (10):743-9
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  375. Claassen DO, Parisi JE, Giannini C, Boeve BF, Dickson DW, Josephs KA. Frontotemporal dementia mimicking dementia with Lewy bodies. Cogn Behav Neurol. 2008 Sep; 21 (3):157-63
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  376. Fujishiro H, Ahn TB, Frigerio R, DelleDonne A, Josephs KA, Parisi JE, Eric Ahlskog J, Dickson DW. Glial cytoplasmic inclusions in neurologically normal elderly: prodromal multiple system atrophy? Acta Neuropathol. 2008 Sep; 116 (3):269-75 Epub 2008 June 14
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  377. Vemuri P, Whitwell JL, Kantarci K, Josephs KA, Parisi JE, Shiung MS, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Jack CR Jr. Antemortem MRI based STructural Abnormality iNDex (STAND)-scores correlate with postmortem Braak neurofibrillary tangle stage. Neuroimage. 2008 Aug 15; 42 (2):559-67 Epub 2008 May 20
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  378. DelleDonne A, Klos KJ, Fujishiro H, Ahmed Z, Parisi JE, Josephs KA, Frigerio R, Burnett M, Wszolek ZK, Uitti RJ, Ahlskog JE, Dickson DW. Incidental Lewy body disease and preclinical Parkinson disease. Arch Neurol. 2008 Aug; 65 (8):1074-80
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  379. Hu WT, Josephs KA, Knopman DS, Boeve BF, Dickson DW, Petersen RC, Parisi JE. Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer disease. Acta Neuropathol. 2008 Aug; 116 (2):215-20 Epub 2008 July 01
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  380. Josephs KA, Lin WL, Ahmed Z, Stroh DA, Graff-Radford NR, Dickson DW. Frontotemporal lobar degeneration with ubiquitin-positive, but TDP-43-negative inclusions. Acta Neuropathol. 2008 Aug; 116 (2):159-67 Epub 2008 June 14
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  381. Milone M, Brunetti-Pierri N, Tang LY, Kumar N, Mezei MM, Josephs K, Powell S, Simpson E, Wong LJ. Sensory ataxic neuropathy with ophthalmoparesis caused by POLG mutations. Neuromuscul Disord. 2008 Aug; 18 (8):626-32 Epub 2008 June 27
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  382. Josephs KA. Frontotemporal dementia and related disorders: deciphering the enigma. Ann Neurol. 2008 Jul; 64(1):4-14.
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  383. Kantarci K, Knopman DS, Dickson DW, Parisi JE, Whitwell JL, Weigand SD, Josephs KA, Boeve BF, Petersen RC, Jack CR Jr. Alzheimer disease: postmortem neuropathologic correlates of antemortem 1H MR spectroscopy metabolite measurements. Radiology. 2008 Jul; 248 (1):210-20
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  384. Fujishiro H, Frigerio R, Burnett M, Klos KJ, Josephs KA, Delledonne A, Parisi JE, Ahlskog JE, Dickson DW. Cardiac sympathetic denervation correlates with clinical and pathologic stages of Parkinson's disease. Mov Disord. 2008 Jun 15; 23 (8):1085-92
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  385. Wider C, Uitti RJ, Wszolek ZK, Fang JY, Josephs KA, Baker MC, Rademakers R, Hutton ML, Dickson DW. Progranulin gene mutation with an unusual clinical and neuropathologic presentation. Mov Disord. 2008 Jun 15; 23 (8):1168-73
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  386. Josephs KA, Whitwell JL, Knopman DS, Hu WT, Stroh DA, Baker M, Rademakers R, Boeve BF, Parisi JE, Smith GE, Ivnik RJ, Petersen RC, Jack CR Jr, Dickson DW. Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype. Neurology. 2008 May 6; 70 (19 Pt 2):1850-7 Epub 2008 Apr 09
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  387. Josephs KA. Review of Frontotemporal dementia syndromes. Journal of Neurology, Neurosurgery & Psychiatry. 2008 May; 79(5):614.
  388. Dickson DW, Fujishiro H, DelleDonne A, Menke J, Ahmed Z, Klos KJ, Josephs KA, Frigerio R, Burnett M, Parisi JE, Ahlskog JE. Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease. Acta Neuropathol. 2008 Apr; 115 (4):437-44 Epub 2008 Feb 09
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  389. Josephs KA, Whitwell JL, Parisi JE, Knopman DS, Boeve BF, Geda YE, Jack CR Jr, Petersen RC, Dickson DW. Argyrophilic grains: a distinct disease or an additive pathology? Neurobiol Aging. 2008 Apr; 29 (4):566-73 Epub 2006 Dec 26
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  390. Keegan BM, Giannini C, Parisi JE, Lucchinetti CF, Boeve BF, Josephs KA. Sporadic adult-onset leukoencephalopathy with neuroaxonal spheroids mimicking cerebral MS. Neurology. 2008 Mar 25; 70(13 Pt 2):1128-33. Epub 2008 Feb 20.
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  391. Czarnecki K, Kumar N, Josephs KA. Parkinsonism and tardive antecollis in frontotemporal dementia--increased sensitivity to newer antipsychotics? Eur J Neurol. 2008 Feb; 15 (2):199-201
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  392. Whitwell JL, Jack CR Jr, Pankratz VS, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Dickson DW, Josephs KA. Rates of brain atrophy over time in autopsy-proven frontotemporal dementia and Alzheimer disease. Neuroimage. 2008 Feb 1; 39 (3):1034-40 Epub 2007 Oct 10
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  393. Josephs KA, Whitwell JL, Ahmed Z, Shiung MM, Weigand SD, Knopman DS, Boeve BF, Parisi JE, Petersen RC, Dickson DW, Jack CR Jr. Beta-amyloid burden is not associated with rates of brain atrophy. Ann Neurol. 2008 Feb; 63 (2):204-12
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  394. Ahmed Z, Josephs KA, Gonzalez J, DelleDonne A, Dickson DW. Clinical and neuropathologic features of progressive supranuclear palsy with severe pallido-nigro-luysial degeneration and axonal dystrophy. Brain. 2008 Feb; 131(Pt 2):460-72. Epub 2007 Dec 24.
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  395. Josephs KA, Whitwell JL, Dickson DW, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Jack CR Jr. Voxel-based morphometry in autopsy proven PSP and CBD. Neurobiol Aging. 2008 Feb; 29 (2):280-9 Epub 2006 Nov 13
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  396. Boeve BF, Josephs KA, Drubach DA. Current and future management of the corticobasal syndrome and corticobasal degeneration. Handb Clin Neurol. 2008; 89:533-48.
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  397. Josephs KA. Clinical aspects of TDP-43 proteinopathy, neurofilament inclusion body disease and dementias lacking distinctive proteinopathy. Handb Clin Neurol. 2008; 89:377-82
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  398. Josephs KA, Whitwell JL, Duffy JR, Vanvoorst WA, Strand EA, Hu WT, Boeve BF, Graff-Radford NR, Parisi JE, Knopman DS, Dickson DW, Jack CR Jr, Petersen RC. Progressive aphasia secondary to Alzheimer disease vs FTLD pathology. Neurology. 2008 Jan 1; 70 (1):25-34
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  399. McKeon A, Josephs KA, Klos KJ, Hecksel K, Bower JH, Michael Bostwick J, Eric Ahlskog J. Unusual compulsive behaviors primarily related to dopamine agonist therapy in Parkinson's disease and multiple system atrophy. Parkinsonism Relat Disord. 2007 Dec; 13(8):516-9. Epub 2007 Jun 04.
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  400. Josephs KA. Capgras syndrome and its relationship to neurodegenerative disease. Arch Neurol. 2007 Dec; 64(12):1762-6.
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  401. Geschwind MD, Josephs KA, Parisi JE, Keegan BM. A 54-year-old man with slowness of movement and confusion. Neurology. 2007 Nov 6; 69(19):1881-7.
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  402. Josephs KA, Dickson DW. Hippocampal sclerosis in tau-negative frontotemporal lobar degeneration. Neurobiol Aging. 2007 Nov; 28(11):1718-22. Epub 2006 Aug 22.
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  403. Hu WT, Mandrekar JN, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Hutton M, Dickson DW, Josephs KA. Clinical features of pathologic subtypes of behavioral--variant frontotemporal dementia. Arch Neurol. 2007 Nov; 64(11):1611-6.
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  404. Josephs KA, Dickson DW. Frontotemporal lobar degeneration with upper motor neuron disease/ primary lateral sclerosis. Neurology. 2007 Oct 30; 69(18):1800-1.
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  405. Hu WT, Parisi JE, Knopman DS, Boeve BF, Dickson DW, Ahlskog JE, Petersen RC, Josephs KA. Clinical features and survival of 3R and 4R tauopathies presenting as behavioral variant frontotemporal dementia. Alzheimer Dis Assoc Disord. 2007 Oct-Dec; 21(4):S39-43.
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  406. Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E, Wood EM, Yu CE, Josephs K, Sorenson E, Womack KB, Weintraub S, Pickering-Brown SM, Schofield PR, Brooks WS, Van Deerlin VM, Snowden J, Clark CM, Kertesz A, Boylan K, Ghetti B, Neary D, Schellenberg GD, Beach TG, Mesulam M, Mann D, Grafman J, Mackenzie IR, Feldman H, Bird T, Petersen R, Knopman D, Boeve B, Geschwind DH, Miller B, Wszolek Z, Lippa C, Bigio EH, Dickson D, Graff-Radford N, Hutton M. Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. Lancet Neurol. 2007 Oct; 6 (10):857-68
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  407. Rascovsky K, Hodges JR, Kipps CM, Johnson JK, Seeley WW, Mendez MF, Knopman D, Kertesz A, Mesulam M, Salmon DP, Galasko D, Chow TW, Decarli C, Hillis A, Josephs K, Kramer JH, Weintraub S, Grossman M, Gorno-Tempini ML, Miller BM. Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions. Alzheimer Dis Assoc Disord. 2007 Oct-Dec; 21(4):S14-8.
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  408. McKeon A, Pittock SJ, Glass GA, Josephs KA, Bower JH, Lennon VA, Ahlskog JE. Whole-body tremulousness: isolated generalized polymyoclonus. Arch Neurol. 2007 Sep; 64 (9):1318-22
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  409. Josephs KA. Frontotemporal lobar degeneration. Neurol Clin. 2007 Aug; 25 (3):683-96, vi
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  410. Whitwell JL, Jack CR Jr, Kantarci K, Weigand SD, Boeve BF, Knopman DS, Drubach DA, Tang-Wai DF, Petersen RC, Josephs KA. Imaging correlates of posterior cortical atrophy. Neurobiol Aging. 2007 Jul; 28 (7):1051-61 Epub 2006 June 23
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  411. Dickson DW, Josephs KA, Amador-Ortiz C. TDP-43 in differential diagnosis of motor neuron disorders. Acta Neuropathol. 2007 Jul; 114: (1)71-9.
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  412. Whitwell JL, Jack CR Jr, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Ferman TJ, Dickson DW, Josephs KA. Rates of cerebral atrophy differ in different degenerative pathologies. Brain. 2007 Apr; 130 (Pt 4):1148-58 Epub 2007 Mar 08
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  413. Frigerrio R, Glass G, Klos K, Ahlskog J. Do Incidental Lewy Body Disease (ILBD) and Parkinson's disease (PD) Have Similar Risk Factor Profiles? An Exploratory Study. Neurology. 2007 Mar 20; 68(Suppl 1):A259.
  414. Whitwell JL, Jack CR Jr, Baker M, Rademakers R, Adamson J, Boeve BF, Knopman DS, Parisi JF, Petersen RC, Dickson DW, Hutton ML, Josephs KA. Voxel-based morphometry in frontotemporal lobar degeneration with ubiquitin-positive inclusions with and without progranulin mutations. Arch Neurol. 2007 Mar; 64 (3):371-6
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  415. Whitwell JL, Weigand SD, Shiung MM, Boeve BF, Ferman TJ, Smith GE, Knopman DS, Petersen RC, Benarroch EE, Josephs KA, Jack CR Jr. Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's disease. Brain. 2007 Mar; 130 (Pt 3):708-19 Epub 2007 Jan 31
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  416. Josephs KA, Ahmed Z, Katsuse O, Parisi JF, Boeve BF, Knopman DS, Petersen RC, Davies P, Duara R, Graff-Radford NR, Uitti RJ, Rademakers R, Adamson J, Baker M, Hutton ML, Dickson DW. Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions with progranulin gene (PGRN) mutations. J Neuropathol Exp Neurol. 2007 Feb; 66 (2):142-51
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  417. Miller BL, Josephs KA, Parisi JE, Keegan BM. A 34-year-old man with progressive behavioral and language disturbance. Neurology. 2007 Jan 2; 68(1):68-74.
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  418. Whitwell JL, Josephs KA. Voxel-based morphometry and its application to movement disorders. Parkinsonism Relat Disord. 2007; 13 Suppl 3:S406-16.
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  419. Klos KJ, Ahlskog JE, Kumar N, Cambern S, Butz J, Burritt M, Fealey RD, Cowl CT, Parisi JE, Josephs KA. Brain metal concentrations in chronic liver failure patients with pallidal T1 MRI hyperintensity. Neurology. 2006 Dec 12; 67(11):1984-9.
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  420. Boeve BF, Baker M, Dickson DW, Parisi JE, Giannini C, Josephs KA, Hutton M, Pickering-Brown SM, Rademakers R, Tang-Wai D, Jack CR Jr, Kantarci K, Shiung MM, Golde T, Smith GE, Geda YE, Knopman DS, Petersen RC. Frontotemporal dementia and parkinsonism associated with the IVS1+1G->A mutation in progranulin: a clinicopathologic study. Brain. 2006 Nov; 129 (Pt 11):3103-14 Epub 2006 Oct 09
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  421. Josephs KA, Whitwell JL, Jack CR, Parisi JE, Dickson DW. Frontotemporal lobar degeneration without lobar atrophy. Arch Neurol. 2006 Nov; 63(11):1632-8.
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  422. Gass J, Cannon A, Mackenzie IR, Boeve B, Baker M, Adamson J, Crook R, Melquist S, Kuntz K, Petersen R, Josephs K, Pickering-Brown SM, Graff-Radford N, Uitti R, Dickson D, Wszolek Z, Gonzalez J, Beach TG, Bigio E, Johnson N, Weintraub S, Mesulam M, White CL 3rd, Woodruff B, Caselli R, Hsiung GY, Feldman H, Knopman D, Hutton M, Rademakers R. Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration. Hum Mol Genet. 2006 Oct 15; 15 (20):2988-3001 Epub 2006 Sept 01
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  423. Klos KJ, Chandler M, Kumar N, Ahlskog JE, Josephs KA. Neuropsychological profiles of manganese neurotoxicity. Eur J Neurol. 2006 Oct; 13(10):1139-41.
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  424. Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Tang-Wai DF, Drubach DA, Jack CR Jr, Petersen RC. Visual hallucinations in posterior cortical atrophy. Arch Neurol. 2006 Oct; 63 (10):1427-32
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  425. Barnes J, Whitwell JL, Frost C, Josephs KA, Rossor M, Fox NC. Measurements of the amygdala and hippocampus in pathologically confirmed Alzheimer disease and frontotemporal lobar degeneration. Arch Neurol. 2006 Oct; 63(10):1434-9.
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  426. Hu WT, Murray JA, Greenaway MC, Parisi JE, Josephs KA. Cognitive impairment and celiac disease. Arch Neurol. 2006 Oct; 63(10):1440-6.
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  427. Baba Y, Putzke JD, Tsuboi Y, Josephs KA, Thomas N, Wszolek ZK, Dickson DW. Effect of MAPT and APOE on prognosis of progressive supranuclear palsy. Neurosci Lett. 2006 Sep 11; 405(1-2):116-9. Epub 2006 Jul 12.
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  428. Glass GA, Josephs KA, Ahlskog JE. Respiratory insufficiency as the primary presenting symptom of multiple-system atrophy. Arch Neurol. 2006 Jul; 63(7):978-81.
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  429. Josephs KA, Duffy JR, Strand EA, Whitwell JL, Layton KF, Parisi JE, Hauser MF, Witte RJ, Boeve BF, Knopman DS, Dickson DW, Jack CR Jr, Petersen RC. Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech. Brain. 2006 Jun; 129 (Pt 6):1385-98 Epub 2006 Apr 13
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  430. Cannon A, Baker M, Boeve B, Josephs K, Knopman D, Petersen R, Parisi J, Dickison D, Adamson J, Snowden J, Neary D, Mann D, Hutton M, Pickering-Brown SM. CHMP2B mutations are not a common cause of frontotemporal lobar degeneration. Neurosci Lett. 2006 May 1; 398 (1-2):83-4 Epub 2006 Jan 23
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  431. Klos KJ, Ahlskog JE, Josephs KA, Apaydin H, Parisi JE, Boeve BF, DeLucia MW, Dickson DW. Alpha-synuclein pathology in the spinal cords of neurologically asymptomatic aged individuals. Neurology. 2006 Apr 11; 66(7):1100-2.
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  432. Josephs KA, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Dickson DW. Clinically undetected motor neuron disease in pathologically proven frontotemporal lobar degeneration with motor neuron disease. Arch Neurol. 2006 Apr; 63(4):506-12.
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  433. Ozawa T, Healy DG, Abou-Sleiman PM, Ahmadi KR, Quinn N, Lees AJ, Shaw K, Wullner U, Berciano J, Moller JC, Kamm C, Burk K, Josephs KA, Barone P, Tolosa E, Goldstein DB, Wenning G, Geser F, Holton JL, Gasser T, Revesz T, Wood NW, European MSA study group. The alpha-synuclein gene in multiple system atrophy. J Neurol Neurosurg Psychiatry. 2006 Apr; 77(4):464-7.
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  434. Josephs KA, Katsuse O, Beccano-Kelly DA, Lin WL, Uitti RJ, Fujino Y, Boeve BF, Hutton ML, Baker MC, Dickson DW. Atypical progressive supranuclear palsy with corticospinal tract degeneration. J Neuropathol Exp Neurol. 2006 Apr; 65 (4):396-405
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  435. Josephs KA, Mandrekar JN, Dickson DW. The relationship between histopathological features of progressive supranuclear palsy and disease duration. Parkinsonism Relat Disord. 2006 Mar; 12(2):109-12. Epub 2005 Dec 06.
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  436. Josephs KA, Matsumoto JY, Ahlskog JE. Benign tremulous parkinsonism. Arch Neurol. 2006 Mar; 63(3):354-7.
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  437. Murali HR, Josephs KA, Wijdicks EF. Guillain-Barre syndrome in an immunocompromised patient and coccidioidomycosis infection. Rev Neurol Dis. 2006 Spring; 3(2):82-4.
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  438. Crum BA, Josephs KA. Varied electrophysiologic patterns in spinocerebellar ataxia type 2. Eur J Neurol. 2006 Feb; 13(2):194-7.
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  439. Josephs KA, Petersen RC, Knopman DS, Boeve BF, Whitwell JL, Duffy JR, Parisi JE, Dickson DW. Clinicopathologic analysis of frontotemporal and corticobasal degenerations and PSP. Neurology. 2006 Jan 10; 66 (1):41-8
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  440. Whitwell JL, Jack CR Jr, Senjem ML, Josephs KA. Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degeneration. Neurology. 2006 Jan 10; 66 (1):102-4
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  441. Josephs KA, Whitwell JL, Boeve BF, Shiung MM, Gunter JL, Parisi JE, Dickson DW, Jack CR. Rates of cerebral atrophy in autopsy-confirmed progressive supranuclear palsy. Ann Neurol. 2006 Jan; 59(1):200-3.
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  442. Shamim A, Siddiqui BK, Josephs KA. The corticobasal syndrome triggered by central pontine myelinolysis. Eur J Neurol. 2006 Jan; 13(1):82-4.
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  443. Ridha B, Josephs KA. Young-onset dementia: a practical approach to diagnosis. Neurologist. 2006 Jan; 12(1):2-13.
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  444. Klos KJ, Josephs KA, Parisi JE, Dickson DW. Alpha-synuclein immunohistochemistry in two cases of co-occurring idiopathic Parkinson's disease and motor neuron disease. Mov Disord. 2005 Nov; 20(11):1515-20.
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  445. Dodd ML, Klos KJ, Bower JH, Geda YE, Josephs KA, Ahlskog JE. Pathological gambling caused by drugs used to treat Parkinson disease. Arch Neurol. 2005 Sep; 62 (9):1377-81 Epub 2005 July 11
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  446. Klos KJ, Ahlskog JE, Josephs KA, Fealey RD, Cowl CT, Kumar N. Neurologic spectrum of chronic liver failure and basal ganglia T1 hyperintensity on magnetic resonance imaging: probable manganese neurotoxicity. Arch Neurol. 2005 Sep; 62(9):1385-90.
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  447. Whitwell JL, Josephs KA, Rossor MN, Stevens JM, Revesz T, Holton JL, Al-Sarraj S, Godbolt AK, Fox NC, Warren JD. Magnetic resonance imaging signatures of tissue pathology in frontotemporal dementia. Arch Neurol. 2005 Sep; 62(9):1402-8.
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  448. Klos KJ, Bower JH, Josephs KA, Matsumoto JY, Ahlskog JE. Pathological hypersexuality predominantly linked to adjuvant dopamine agonist therapy in Parkinson's disease and multiple system atrophy. Parkinsonism Relat Disord. 2005 Sep; 11 (6):381-6
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  449. Josephs KA, Knopman DS, Whitwell JL, Boeve BF, Parisi JE, Petersen RC, Dickson DW. Survival in two variants of tau-negative frontotemporal lobar degeneration: FTLD-U vs FTLD-MND. Neurology. 2005 Aug 23; 65(4):645-7.
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  450. Ridha BH, Josephs KA, Rossor MN. Delusions and hallucinations in dementia with Lewy bodies: Worsening with memantine. Neurology. 2005 Aug 9; 65(3):481-2.
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  451. Josephs KA, Boeve BF, Duffy JR, Smith GE, Knopman DS, Parisi JE, Petersen RC, Dickson DW. Atypical progressive supranuclear palsy underlying progressive apraxia of speech and nonfluent aphasia. Neurocase. 2005 Aug; 11 (4):283-96
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  452. Tsuboi Y, Josephs KA, Boeve BF, Litvan I, Caselli RJ, Caviness JN, Uitti RJ, Bott AD, Dickson DW. Increased tau burden in the cortices of progressive supranuclear palsy presenting with corticobasal syndrome. Mov Disord. 2005 Aug; 20(8):982-8.
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  453. Godbolt AK, Josephs KA, Revesz T, Warrington EK, Lantos P, King A, Fox NC, Al Sarraj S, Holton J, Cipolotti L, Khan MN, Rossor MN. Sporadic and familial dementia with ubiquitin-positive tau-negative inclusions - Clinical features of one histopathological abnormality underlying frontotemporal lobar degeneration. Arch Neurol. 2005 Jul; 62(7):1097-101.
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  454. Hu WT, Josephs KA, Ahlskog JE, Shin C, Boeve BF, Witte RJ. MRI correlates of alien leg-like phenomenon in corticobasal degeneration. Mov Disord. 2005 Jul; 20(7):870-3.
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  455. Josephs KA, Ahlskog JE, Klos KJ, Kumar N, Fealey RD, Trenerry MR, Cowl CT. Neurologic manifestations in welders with pallidal MRI T1 hyperintensity. Neurology. 2005 Jun 28; 64(12):2033-9. Epub 2005 May 11.
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  456. Rippon GA, Boeve BF, Parisi JE, Dickson DW, Ivnik RI, Jack CR, Hutton M, Baker M, Josephs KA, Knopman DS, Petersen RC. Late-onset frontotemporal dementia associated with progressive supranuclear palsy/argyrophilic grain disease/Alzheimer's disease pathology. Neurocase. 2005 Jun; 11(3):204-11.
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  457. Matthews BR, Jones LK, Saad DA, Aksamit AJ, Josephs KA. Cerebellar ataxia and central nervous system whipple disease. Arch Neurol. 2005 Apr; 62(4):618-20.
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  458. Josephs KA, Uchikado H, McComb RD, Bashir R, Wszolek Z, Swanson J, Matsumoto J, Shaw G, Dickson DW. Extending the clinicopathological spectrum of neurofilament inclusion disease. Acta Neuropathol (Berl). 2005 Apr; 109: (4)427-32.
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  459. Stead M, Josephs KA. Successful treatment of status migrainosus after electroconvulsive therapy with dihydroergotamine. Headache. 2005 Apr; 45(4):378-80.
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  460. Knopman DS, Boeve BF, Parisi JE, Dickson DW, Smith GE, Ivnik RJ, Josephs KA, Petersen RC. Antemortem diagnosis of frontotemporal lobar degeneration. Ann Neurol. 2005 Apr; 57 (4):480-8
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  461. Janseen JC, Schott JM, Cipolotti L, Fox NC, Scahill RI, Josephs KA, Stevens JM, Rossor MN. Mapping the onset and progression of atrophy in familial frontotemporal lobar degeneration. J Neurol Neurosurg Psychiatry. 2005 Feb; 76(2):162-8.
  462. Josephs KA, Matsumoto JY, Lindor NM. Heterozygous Niemann-Pick disease type C presenting with tremor. Neurology. 2004 Dec 14; 63 (11):2189-90
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  463. Josephs KA, Tang-Wai DF, Edland SD, Knopman DS, Dickson DW, Parisi JE, Petersen RC, Jack CR, Boeve BF. Correlation between antemortem magnetic resonance Imaging findings and pathologically confirmed corticobasal degeneration. Arch Neurol. 2004 Dec; 61(12):1881-4.
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  464. Paviour DC, Lees AJ, Josephs KA, Ozawa T, Ganguly M, Strand C, Godbolt A, Howard RS, Revesz T, Holton JL. Frontotemporal lobar degeneration with ubiquitin-only-immunoreactive neuronal changes: broadening the clinical picture to include progressive supranuclear palsy. Brain. 2004 Nov; 127(Part 11):2441-51.
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  465. Josephs KA, Silber MH, Fealey RD, Nippoldt TB, Auger RG, Vernino S. Neurophysiologic studies in Morvan syndrome. J Clin Neurophysiol. 2004 Nov-Dec; 21 (6):440-5
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  466. Ozawa T, Paviour D, Quinn NP, Josephs KA, Sangha H, Kliford L, Healy DG, Wood NW, Lees AJ, Holton JL, Rvesz T. The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations. Brain. 2004 Oct 27; Epub ahead of print.
  467. Josephs KA, Tsuboi Y, Cookson N, Watt H, Dickson DW. Apolipoprotein E epsilon 4 is a determinant for Alzheimer-type pathologic features in tauopathies, synucleinopathies, and frontotemporal degeneration. Arch Neurol. 2004 Oct; 61(10):1579-84.
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  468. Josephs KA, Holton JL, Rossor MN, Godbolt AK, Ozawa T, Strand K, Khan N, Al-Sarraj S, Revesz T. Frontotemporal lobar degeneration and ubiquitin immunohistochemistry. Neuropathol Appl Neurobiol. 2004 Aug; 30 (4):369-73
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  469. Josephs KA, Rubino FA, Dickson DW. Nonvasculitic autoimmune inflammatory meningoencephalitis. Neuropathology. 2004 Jun; 24 (2):149-52
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  470. Josephs KA, Tsuboi Y, Dickson DW. Creutzfeldt-Jakob disease presenting as progressive supranuclear palsy. Eur J Neurol. 2004 May; 11(5):343-6.
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  471. Josephs KA, Rossor MN. Alien Hand Syndrome. Practical Neurology. 2004; 4(1):44-55.
  472. Whitwell JL, Warren JD, Josephs KA, Godbolt AK, Revesz T, Fox NC, Rossor MN. Voxel-based morphometry in tau-positive and tau-negative frontotemporal lobar degenerations. Neurodegener Dis. 2004; 1(4-5):225-30.
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  473. Tang-Wai DF, Josephs KA. Diagnosis and Management of Dementia in Parkinson's Disease. Geriatrics and Aging. 2004; 7(10):49-54.
  474. Josephs KA, Jones AG, Dickson DW. Hippocampal sclerosis and ubiquitin-positive inclusions in dementia lacking distinctive histopathology. Dem and Geriatric Cog Dis. 2004; 17(4):342-5.
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  475. Tang-Wai DF, Josephs KA, Boeve BF, Dickson DW, Parisi JE, Petersen RC. Pathologically confirmed corticobasal degeneration presenting with visuospatial dysfunction. Neurology. 2003 Oct 28; 61 (8):1134-5
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  476. Josephs KA, Holton JL, Rossor MN, Braendgaard H, Ozawa T, Fox NC, Petersen RC, Pearl GS, Ganguly M, Rosa P, Laursen H, Parisi JE, Waldemar G, Quinn NP, Dickson DW, Revesz T. Neurofilament inclusion body disease: a new proteinopathy? Brain. 2003 Oct; 126 (Pt 10):2291-303 Epub 2003 July 22
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  477. Josephs KA, Dickson DW. Diagnostic accuracy of progressive supranuclear palsy in the Society for Progressive Supranuclear Palsy brain bank. Mov Disord. 2003 Sep; 18 (9):1018-26
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  478. Tsuboi Y, Slowinski J, Josephs KA, Honer WG, Wszolek ZK, Dickson DW. Atrophy of superior cerebellar peduncle in progressive supranuclear palsy. Neurology. 2003 Jun 10; 60(11):1766-9.
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  479. Josephs KA, Tang Wai DF, Parisi JE. Hippocampal sclerosis in a case of Alzheimer's disease-like dementia with late onset intractable epilepsy. Eur J Neurol. 2003 May; 10(3):333-4.
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  480. Josephs KA, Van Gerpen MW, Van Gerpen JA. Adult onset Niemann-Pick disease type C presenting with psychosis. J Neurol Neurosurg Psychiatry. 2003 Apr; 74 (4):528-9
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  481. Tsuboi Y, Josephs KA, Cookson N, Dickson DW. APOE E4 is a determinant for Alzheimer type pathology in progressive supranuclear palsy. Neurology. 2003 Jan 28; 60 (2):240-5
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  482. Josephs KA, Ishizawa T, Tsuboi Y, Cookson N, Dickson DW. A clinicopathological study of vascular progressive supranuclear palsy: a multi-infarct disorder presenting as progressive supranuclear palsy. Arch Neurol. 2002 Oct; 59 (10):1597-601
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  483. Josephs KA, Parisi JE, Dickson DW. Alpha-synuclein studies are negative in postencephalic parkinsonism of von Economo. Neurology. 2002 Aug 27; 59 (4):645-6
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  484. Travis LH, Josephs KA, Bower JH. 25-year-old woman with incoordination and decreased balance. Mayo Clin Proc. 2001 May; 76(5):551-4.
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  485. Flemming KD, Josephs K, Wijdicks EF. Enlarging vertebrobasilar dolichoectasia with subarachnoid hemorrhage heralded by recurrent ischemia. Case illustration. J Neurosurg. 2000 Mar; 92: (3)504.
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