Search Results 11-20 of 16158 for brca1%20and%20brca2%20genes%20and%20breast%20cancer

  1. Researchers resolve uncertainty in BRCA2 testing, improving cancer risk assessment and patient care - Mayo Clinic News Network

    Many people with VUS may be notified about the reclassification of their VUS as the ClinVar BRCA1/2 expert panel and testing laboratories use the new ...

  2. Mastectomy Surgery in Patients with BRCA Gene Mutations - Mayo Clinic

    James W. Jakub, M.D., Breast Surgeon, Mayo Clinic: Patients with a genetic mutation that increase the risk of developing breast cancer have many options to ...

  3. Triple-Negative Breast Cancer Patients Should Undergo Genetic Screening - Mayo Clinic News Network

    Of these, 11 percent had mutations in the BRCA1 and BRCA2 genes and the rest had mutations in 15 other predisposition genes, including the DNA repair genes ...

  4. Breast cancer chemoprevention: Drugs that reduce risk - Mayo Clinic

    Preventive medicines can reduce breast cancer risk. Learn about how these medicines work, who should consider taking them, and their side effects and health ...

  5. Genetic testing for breast cancer: Psychological and social impact - Mayo Clinic

    Here are some things to think about as you decide whether genetic testing for BRCA1, BRCA2 or the many other genes related to breast cancer is right for you.

  6. A Study To Compare Two Surgical Procedures In Women With BRCA1 Mutations To Assess Reduced Risk Of Ovarian Cancer - Mayo Clinic

    This study may help doctors determine if the two surgical procedures are nearly the same for ovarian cancer risk reduction for women with BRCA1 mutations.

  7. A Study To Test Adding Pembrolizumab To Olaparib Alone As Therapy For Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations - Mayo Clinic

    The primary purpose of this study is to evaluate the progression free survival (PFS) of advanced pancreatic cancer patients with germline BRCA1 or BRCA2 ...

  8. Precision medicine for breast cancer - Mayo Clinic

    The most well-known DNA changes related to breast cancer are BRCA1 and BRCA2. People with these DNA changes have a very high risk of breast cancer and other ...

  9. Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations. - Mayo Clinic

    Germline mutation in BRCA1 or BRCA2 that is predicted to be deleterious or suspected deleterious. · Histologically or cytologically confirmed breast cancer with ...

  10. Assessment Of The Efficacy And Safety Of Olaparib Monotherapy Versus Physicians Choice Chemotherapy In The Treatment Of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations. - Mayo Clinic

    Germline mutation in BRCA1 or BRCA2 that is predicted to be deleterious or suspected deleterious. · Histologically or cytologically confirmed breast cancer with ...