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Dr. Barry's team engineers new ways to get genes into cells and amplify those genes and the proteins that they produce. They've most recently applied this to SARS-CoV-2 using novel vaccine vectors called single-cycle adenoviruses being studied in Phase 1 clinical trials.
The Vector and Vaccine Engineering Lab at Mayo Clinic develops therapeutics and vaccines that target specific cells.
The lab's aims include enhancing the specificity of vectors to cells and improving the ability of vaccines to protect against conditions including HIV-1, influenza and bioweapons.