Dr. Mukhopadhyay leads six main research projects in the Tumor Angiogenesis and Vascular Biology Lab. Explore our research projects and related research images:
- Dopamine in angiogenesis, immunity and lung tumor progression. We're investigating how the neurotransmitter dopamine affects the ability of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) to act in lung tumors. Read more.
- GIPC in cancer therapeutics. In this project, we're studying peptides and small molecules that inhibit GAIP-interacting protein C terminus (GIPC). Read more.
- Targeting VEGF-independent proangiogenic pathways in anti-VEGF refractory renal cell cancer. We're examining how vascular endothelial growth factor (VEGF) pathways can be targeted to treat tumors that have developed resistance to anti-VEGF therapies. Read more.
- Regulation of FIH expression in renal cancer. Our team is exploring how hypoxia inducible factor-1/2 HIF-1/2 α (HIF-1/2α) regulates the expression of factor inhibitors for hypoxia (FIH) in renal cell carcinoma. Read more.
- Role of Neuropilin-1 in pathogenesis of cardiovascular diseases. We're investigating the role of neuropilin-1 (NRP1) in the pathogenesis of cardiovascular diseases. Read more.
- Role of VEGF signaling in vascular permeability and the zebrafish disease model. In this project, we're using a zebrafish disease model to study vascular endothelial growth factor (VEGF) signaling in vascular permeability. Read more.
- Research images. Our research images show how we use wild-type and knockout murine models and zebrafish models to study the effect of proteins on vascular permeability, angiogenesis and heart morphology. Read more.