Dr. Savastano testing new material Advancing horizons in neurosurgery

Dr. Savastano's lab brings together physician-innovators, biomedical scientists and engineers to conduct trailblazing research and develop new knowledge, tools and techniques in neurosurgery. We are striving to bring new standards of care for neurosurgical diseases by employing a bed-to-bench-to-bed paradigm.


The Translational Neurosurgery and Biotechnology Laboratory is focused on taking unmet clinical needs and problems to the bench and bringing back meaningful solutions to the bedside by ideating, developing, testing, validating and establishing new neurosurgical techniques and technologies.

To accomplish this, our laboratory:

  • Conducts clinical research to identify unmet clinical needs
  • Engages in basic science research to unravel the mechanism of disease or the root cause of current technical failures
  • Employs creative thinking to envision new techniques and devices
  • Turns the vision into reality by developing, testing and optimizing the most advanced biotechnologies and cutting-edge neurosurgical procedures using high-fidelity preclinical models (phantoms, human cadavers and in-vivo models)
  • Collaborates with industry to ensure that a medical device is driven to production, making ideation-to-introduction of novel tools and techniques a reality in the shortest possible time

About Dr. Savastano

Luis E. Savastano, M.D., Ph.D., is a hybrid cerebrovascular neurosurgeon, specializing in the microsurgical and endovascular treatment of brain aneurysm, moyamoya disease, brain and spinal arteriovenous malformations (AVMs), carotid artery disease, and stroke at Mayo Clinic in Rochester, Minnesota. He is also an assistant professor of neurosurgery at Mayo Clinic College of Medicine and Science. Dr. Savastano's research is focused on understanding, diagnosing and treating patients with cerebrovascular diseases.