Neuroimaging of Alzheimer's Disease
As a neuropathologist, Dr. Murray's studies intervene at study participants' last time-point (autopsy). However, there is much information that can be used to benefit people living with Alzheimer's disease by understanding the neuropathologic underpinnings of neuroimaging changes. Ongoing projects are investigating the target of multimodal imaging modalities, including tau positron emission tomography and structural magnetic resonance imaging. The overall goal is to design an imaging-based algorithm that recapitulates the neuropathologic patterns toward the effort of earlier diagnosis of atypical Alzheimer's disease.
This work is supported by funding from the National Institute on Aging.