Optimal Benefits From Surgery

When a person has a glioblastoma, typically the best initial course of action is to remove as much of the tumor in the brain as possible. However, this is risky because the tumor cells are mixed with healthy brain cells.

Dr. Swanson's research team in her Mathematical Neuro-Oncology Lab is working in collaboration with physicians at the Cleveland Clinic to define the optimal surgical goal for each person with glioblastoma. In this project, a large set of data from an independent phase III clinical trial is being utilized to see if individual tumor kinetics, as estimated through a mathematical model developed by the research team, can identify those who will significantly benefit from maximal tissue removal.