Current projects of the Cholestatic Liver Diseases Laboratory include:

  • Studying the genetic predisposition and risk factors for the development and prognosis of primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC)
  • Understanding the molecular pathogenesis of primary sclerosing cholangitis and cholangiocarcinoma to develop evidence-based clinical trials of promising medical therapies
  • Identifying effective biomarkers and strategies for early detection of cholangiocarcinoma and prognostication of disease course for PSC and PBC