Imaging of Stem Cell Biology After Transplant
With this research project on stem cell biology imaging, our lab is developing imaging strategies to help improve understanding of the biology of stem cells after transplantation. Our overall goal is to develop and use new imaging strategies to assess the efficacy of cardiac gene and cell therapy.
Findings from our biological studies will be used to design improved therapeutic strategies for cardiovascular diseases.
Our research team has optimized reporter gene-imaging methods to monitor the fate of transplanted stem cells and gained a better understanding of some of the factors that affect their survival. In addition, we have led studies translating these studies to large animal models.
Our lab is particularly interested in the role that the myocardial microenvironment plays in the biology and survival of transplanted stem cells. Read more about stem cells.