Understanding Atherosclerosis Through Molecular Imaging

In this research project, our lab is developing molecular imaging methods to detect arterial atherosclerotic lesions.

Untreated, arterial atherosclerotic lesions can evolve into more-severe obstructions and lead to life-threatening vascular problems, such as myocardial infarction, stroke or peripheral arterial disease. Read more about atherosclerosis.

Under the direction of Dr. Rodriguez-Porcel, our research team is studying atherosclerosis using a wide array of molecular imaging technologies, such as nuclear cardiology and ultrasound, which are providing an improved and more accurate study of the biology of atherosclerotic disease.

As part of the atherosclerosis molecular imaging project, we're developing novel imaging devices and improving existing ones. For example, our team is constructing a novel intravascular catheter to detect the metabolic activity of atherosclerotic plaque, which will provide critical information about which plaques are more prone to rupture and cause myocardial infarction.

Translation of these strategies will represent a significant advance in the understanding and treatment of patients, and if we're able to detect and treat atherosclerotic plaques, the incidence of myocardial infarctions in these patients might be reduced.