Evaluations at the tissue level are critical to musculoskeletal research. The Bone Histomorphometry Lab in the Department of Orthopedics has a rich history of conducting such "in situ" evaluations in both human and animal tissue. The primary expertise of the Bone Histo Lab is the processing of skeletal tissue in its calcified state for the preparation of histology slides.

Quantification of skeletal parameters in these tissue sections can be performed with a bone-specific image analysis system and a microscope, which is also equipped with ultraviolet lighting. Being able to assess bone volume and how it is regulated, can lead to the identification of skeletal pathologies and the evaluation of potential countermeasures.