Genetic Epidemiology of CLL Consortium Study

Study overview

The Genetic Epidemiology of CLL Consortium Study is an observational study that investigates the genetic basis of chronic lymphocytic leukemia.

Chronic lymphocytic leukemia (CLL) exhibits one of the strongest familial tendencies of all the lymphoproliferative disorders. Because of this, the B-Cell Lymphoproliferative Disorders Laboratory is studying the genetic origins of CLL through the participation of high-risk CLL families.

This study is conducted through a multicenter, multidisciplinary consortium called the Genetic Epidemiology of CLL (GEC) Consortium, in which Dr. Slager and her lab participate.

The GEC Consortium Study is funded by the National Cancer Institute (U01 CA 118444) and includes investigators from Mayo Clinic; MD Anderson Cancer Center; the National Cancer Institute; the University of California, San Diego; the University of Minnesota; Duke University; CancerCare Manitoba, and the University of Utah.

This family-based research resource allows Dr. Slager's lab to develop a study population enriched for genetic exposures, positioning the research team to characterize the genetic risk of chronic lymphocytic leukemia.

Study eligibility

To join the CLL study, a family must have:

  • A living patient with a diagnosis of CLL
  • A blood relative (alive or deceased) diagnosed with CLL

Study requirements

Families interested in the Genetic Epidemiology of CLL Consortium Study don't need to visit a study site to participate. The study pays for any costs associated with participation, including blood draws, and sends related questionnaires.

Participation in the CLL study includes:

  • Completing a questionnaire detailing the family history of cancer.
  • Completing a questionnaire about lifestyle factors, personal medical history and demographic information.
  • Donating a small amount of blood, about 4 tablespoons. For your convenience, we can send you a kit that you can take to your local clinic or doctor for the blood draw. You can also have this done at Mayo Clinic.
  • Donating a sample of saliva. A kit will be mailed to you with all the items to collect the sample.
  • Providing permission with written informed consent to access, for research purposes only, any medical records related to care for blood or lymph node cancer or related conditions.

Study contact

For more information or to participate in the Genetic Epidemiology of CLL Consortium Study, contact:

Catherine (Catie) A. Erding