Family Study of CLL and Other Lymphoproliferative Disorders

The Family Study of CLL and Other Lymphoproliferative Disorders is an observational study that investigates the genetic basis of chronic lymphocytic leukemia.

Chronic lymphocytic leukemia (CLL) exhibits one of the strongest familial tendencies of all the lymphoproliferative disorders. Because of this, the B-Cell Lymphoproliferative Disorders Laboratory is studying the genetic origins of CLL through the participation of high-risk CLL families.

This family-based research resource allows Dr. Slager's lab to develop a study population enriched for genetic exposures, positioning the research team to characterize the genetic risk of chronic lymphocytic leukemia.

Study eligibility

To join the CLL study, a family must have:

  • A living patient with a diagnosis of CLL
  • A blood relative (alive or deceased) diagnosed with CLL

Study requirements

Families interested in the Family Study of CLL and Other Lymphoproliferative Disorders don't need to visit a study site to participate. The study pays for any costs associated with participation, including blood draws, and sends related questionnaires.

Participation in the CLL study includes:

  • Completing a questionnaire detailing the family history of cancer.
  • Completing a questionnaire about lifestyle factors, personal medical history and demographic information.
  • Donating a small amount of blood, about 4 tablespoons (59 ml). For your convenience, we can send you a kit that you can take to your local clinic or doctor for the blood draw. You can also have this done at Mayo Clinic.
  • Donating a sample of saliva. A kit will be mailed to you with all the items to collect the sample.
  • Providing permission with written informed consent to access, for research purposes only, any medical records related to care for blood or lymph node cancer or related conditions.