Rochester, Minnesota


Warner.Nafisseh@mayo.edu Clinical Profile


Nafisseh S. Warner, M.D., studies the associations of pain and opioids with cognitive decline in older adults. Her research interests include pain management and neurocognitive outcomes in the aging population, with the goal of optimizing pain treatment outcomes in older adults while minimizing adverse effects.

Focus areas

  • Exploring the associations among prescription opioids, cognitive function and brain structure in older adults.
  • Analyzing the relationships between pain and cognition in older adults.
  • Evaluating longitudinal trends in opioid and nonopioid analgesic use in the aging population.
  • Understanding patient perceptions and barriers to opioid use and its impact on cognition.

Significance to patient care

Chronic pain is prevalent in older adults, and prescription opioids are often used to treat pain in this population. It is critically important to understand the long-term effects of prescription opioid use in older adults. Also important is the development of pain pathways that minimize side effects while maximizing patient-specific health goals.

Professional highlights

  • Assistant editor, Anesthesia & Analgesia, 2022-present.
  • Pain Medicine, 2022-present.
    • Associate editor, Pain & Aging Section
    • Social media editor
  • K23 grant, National Institute on Aging, 2020-present.
  • Kern Health Care Delivery Scholar, Mayo Clinic, 2019-2022.


Primary Appointment

  1. Consultant, Department of Anesthesiology and Perioperative Medicine

Academic Rank

  1. Associate Professor of Anesthesiology


  1. Mayo Clinic Scholar - Division of Pain Medicine Department of Anesthesiology and Perioperative Medicine
  2. Fellow Pain Medicine, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. Resident Anesthesiology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  4. Residency - Transitional Year Gundersen-Lutheran Medical Center
  5. MD Mayo Clinic Alix School of Medicine
  6. Fellowship - Clinical Research University of Texas Southwestern Medical Center
  7. Masters - ScM, Biochemistry and Molecular Biology The Johns Hopkins University Bloomberg School of Public Health
  8. BS - Molecular and Cellular Biology University of Arizona

Clinical Studies

Learn about clinical trials that address specific scientific questions about human health and disease.

See my studies.

Explore all research studies at Mayo Clinic.


See the peer-reviewed findings I have published as a result of my research.

Review publications.

Mayo Clinic Footer