Rochester, Minnesota Clinical Profile


Andre Terzic, M.D., Ph.D., pioneered regenerative medicine at Mayo Clinic. He has led the development of next-generation regenerative solutions, including first-in-class products for heart repair. He leads team science to discover genes for dilated cardiomyopathy and atrial fibrillation.

Dr. Terzic has written more than 450 publications advancing diagnostic and therapeutic strategies for heart failure. His scientific manuscripts have been cited more than 10,000 times.

Focus areas

  • Regenerative medicine and stem cell biology.
  • Cardioprotection.
  • Heart failure.
  • Genetics of cardiac disease and stress tolerance.
  • Bioenergetic signaling, nucleocytoplasmic communication and ion channel biology.

Significance to patient care

Dr. Terzic's research program uses new technologies to transform many different forms of treatment, from palliative measures to cures. His work has advanced cardiovascular care by enabling personalized early risk detection and treatment. Dr. Terzic's research has made it possible for healthcare professionals to define people's unique risk of cardiovascular disease based on their specific genes and metabolism. Additionally, his work helps clinicians personalize treatments for people with targeted drug- or stem cell-based repair.

Some of Dr. Terzic's specific contributions include:

  • Advancing the development of safer cardioplegia.
  • Improving drug selection for people who have diabetes.
  • Refining diagnostic and management strategies for individuals with heart failure or ischemic heart disease, which is prevalent in aging populations.

Professional highlights

  • Marriott Family Director, Comprehensive Cardiac Regenerative Medicine for the Center for Regenerative Biotherapeutics (formerly the Center for Regenerative Medicine), Mayo Clinic, 2014-present.
  • Board of directors, Mayo Collaborative Services, 2013-present.
  • Chair, Scientific Advisory Board, International Society for Cardiovascular Translational Research, 2010-present.
  • Chair, Discovery-Translation Scientific Advisory Board, Mayo Clinic, 2005-present.
  • Director, National Institutes of Health-National Research Service Award, Health Cardiovasology Program, Mayo Clinic, 2004-present.
  • Director, J. Willard Jr. and Donna Marriott Heart Disease Research Program, 2001-present.
  • Distinguished Mayo Clinic Investigator, Mayo Clinic, 2023.
  • Michael S. and Mary Sue Shannon Family Director for Regenerative Medicine, Center for Regeneration Biotherapeutics, Mayo Clinic, 2011-2021.
  • Chair, Council on Functional Genomics and Translational Biology, American Heart Association, 2016-2018.
  • Benedict R. Lucchesi Distinguished Lectureship in Cardiac Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2013.
  • Marriott Family Professor of Cardiovascular Research, Mayo Clinic, 2013.
  • Excellence in Clinical Pharmacology Award, PhRMA Foundation, 2012.
  • Ueda Memorial Award, Japanese Society of Electrocardiology, 2012.
  • American Society for Clinical Pharmacology and Therapeutics:
    • Henry W. Elliott Distinguished Service Award, 2011.
    • President, 2004-2005.
  • Martin E. Rehfuss Medal in Medicine, Jefferson Medical College of Thomas Jefferson University, 2010.


Primary Appointment

  1. Director, Mayo Clinic Center for Regenerative Medicine
  2. Consultant, Division of Heart Rhythm Services, Department of Cardiovascular Medicine

Joint Appointment

  1. Consultant, Department of Molecular Pharmacology and Experimental Therapeutics

Academic Rank

  1. Professor of Medicine
  2. Professor of Pharmacology


  1. Research Associate - Research Associate, Cardiovascular Diseases Mayo Clinic in Rochester
  2. Fellow - Clinical Pharmacology Thomas Jefferson University
  3. PhD - Department of Pharmacology University of Illinois
  4. Fellow - Visiting Scientist & Postdoctoral Fellow French National Institute of Health
  5. Fellow - Graduate College Fellow, Pharmacology University of Illinois at Chicago
  6. Internship - Clinical Center University of Belgrade
  7. MD University of Belgrade

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