Location

Rochester, Minnesota

Contact

Nabzdyk.Christoph@mayo.edu Clinical Profile

SUMMARY

Christoph G. Nabzdyk, M.D., provides anesthesia and critical care for a broad range of surgical patients. His research aims to address the long-standing clinical challenges he encounters such as perioperative hemorrhage, failure of surgical organ repair, and medical device-related thromboembolic and infectious complications. In particular, Dr. Nabzdyk collaborates with Massachusetts Institute of Technology engineers to develop novel biomaterials to tackle clinical challenges and translate these potentially lifesaving technologies into clinical application.

Focus areas

  • Bioadhesive patch for instant air- and liquid-tight organ sealing. Dr. Nabzdyk is developing a hydrogel adhesive technology that can instantly seal organs.
  • Bioadhesive paste for instant hemostasis. Dr. Nabzdyk is developing a bioadhesive paste that can instantly create hemostasis even in high-blood-loss scenarios.
  • Medical device hydrogel coating. Dr. Nabzdyk is developing an ultrathin hydrogel coating that reduces blood flow resistance and features thromboresistant and antifouling properties.

Significance to patient care

Breakdown of surgical organ repair is a feared complication with grave consequences for patients. Despite decades of research, no satisfactory technology is currently available to address this. The bioadhesive patch may offer a simple, off-the-shelf solution for many surgical patients.

Likewise, ensuring perioperative hemostasis can be challenging given existing treatment modalities. The bioadhesive paste may offer a potent alternative to commercially available products to achieve hemostasis even in complex clinical scenarios. This may be of particular help in trauma patients and other patients at high risk of significant blood loss.

With an aging population and improvements in medical device capabilities, an increasing number of patients are dependent on implanted medical devices. However, implanted devices are prone to infections, and intravascular devices are nidi for thrombus formation. Therefore, developing device surfaces that mitigate the risk of some of the most significant complications associated with medical device implantation would have great significance to a broad range of patients.

PUBLICATIONS

See my publications

PROFESSIONAL DETAILS

Primary Appointment

  1. Senior Associate Consultant, Department of Anesthesiology and Perioperative Medicine

Academic Rank

  1. Assistant Professor of Anesthesiology

EDUCATION

  1. Fellowship - Cardiothoracic Anesthesiology Massachusetts General Hospital, Harvard Medical School
  2. Fellowship - Critical Care Medicine Massachusetts General Hospital, Harvard Medical School
  3. Resident - Department of Anesthesiology, Perioperative and Pain Management Brigham and Women's Hospital, Harvard Medical School
  4. Postdoctoral Scholar - Tissue Engineering and Wound Healing Laboratory Brigham and Women's Hospital, Harvard Medical School
  5. Resident - Categorical General Surgery Tufts Medical Center, Tufts School of Medicine
  6. Postdoctoral Research Fellowship - Vascular Surgery Beth Israel Deaconess Medical Center, Harvard Medical School
  7. Postdoctoral Research Fellowship - Laboratory for Accelerated Vascular Research University of California San Francisco Medical Center
  8. Doktor der Medizin - Research Doctorate Defense for German "Dr. med.", "Magna cum laude". Charite University Medicine, Medical College of Humboldt and Free University Berlin
  9. MD Charite University Medicine, Medical College of Humboldt and Free University Berlin
  10. Research Scholar - Cardiovascular Genetics (Position: part-time) Max Planck Institute for Molecular Genetics
  11. Visiting Scholar Tulane University, Section of Cardiology and MD Anderson Cancer Center, Department of Pathology
  12. Research Scholar Tulane University, Section of Cardiology
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BIO-20484871

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